Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka 812-8582, Japan.
Trends Microbiol. 2013 Jul;21(7):320-4. doi: 10.1016/j.tim.2013.05.004. Epub 2013 Jun 11.
RNA viruses evolve rapidly under selection pressure as a result of the high error rates of viral RNA polymerase. 'Cooperation' between wild type and variant measles virus (MV) genomes through the heterooligomer formation of a viral protein has recently been shown to act as a mechanism of viral evolution. This type of cooperation between genomes producing a new phenotype may have implications for various aspects of evolution, including the expansion of viral tropism and host range, the emergence of segmented viral genomes, and the evolution of heteromultimeric molecules. It also lends support to the concept of the quasispecies acting as a unit of selection.
RNA 病毒在选择压力下迅速进化，这是由于病毒 RNA 聚合酶的高错误率所致。最近已经证明，通过病毒蛋白的异源寡聚体形成，野生型和变异型麻疹病毒 (MV) 基因组之间的“合作”是病毒进化的一种机制。这种产生新表型的基因组之间的合作可能对进化的各个方面都有影响，包括病毒嗜性和宿主范围的扩大、分段病毒基因组的出现以及异源多聚分子的进化。它也支持了准种作为选择单位的概念。
