Micheli L J
Clin Orthop Relat Res. 1975 May(108):191-5. doi: 10.1097/00003086-197505000-00031.
Six cases of thromboembolic complications in patients being treated with plaster cast immobilization for a variety of injuries to the lower extremity were encountered over a four month period on an Air Force orthopaedic service. These injuries, consisting of three ruptures of the tendo achillis, two fractures of the tibia, and a sub-talar dislocation of the foot, resulted in one death from pulmonary emboli and three other serious complications of pulmonary emboli. The literature on thromboembolic complications following lower extremity injuries (including information of pathogenesis, clinical characteristics and epidemiology of venous thromboembolism and the hazards of lowere extremity cast immobilization in an individual susceptible to his complication) suggests that prophylaxis against thrombosis should be instituted in high risk individuals who must undergo case immobilization for injuries to the lower extremity.
在空军骨科服务部门的四个月期间，遇到了6例因下肢各种损伤接受石膏固定治疗的患者发生血栓栓塞并发症的情况。这些损伤包括3例跟腱断裂、2例胫骨骨折和1例距下关节脱位，导致1例因肺栓塞死亡，另外3例出现严重的肺栓塞并发症。关于下肢损伤后血栓栓塞并发症的文献（包括静脉血栓栓塞的发病机制、临床特征和流行病学信息以及下肢石膏固定对易患该并发症个体的危害）表明，对于因下肢损伤必须接受石膏固定的高危个体，应采取预防血栓形成的措施。
