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经导管动脉导管未闭封堵术:槟城医院的经验

Transcatheter Closure of Patent Ductus Arteriosus: The Penang Hospital's Experience.

作者信息

Amir Hamzah A R, Tiow C A, Koh G T, Sharifah A M

机构信息

Penang Hospital, Paediatric, Penang Hospital, Jalan Residensi, Georgetown, 10990 Penang, Malaysia.

出版信息

Med J Malaysia. 2011 Mar;66(1):19-21.

Abstract

Transcatheter closure of small and moderate sizes of Patent Ductus Arteriosus (PDA) is a standard and well accepted form of treatment. The aim of this study is to describe the experience of transcatheter closure of PDA in Penang Hospital. All patients who underwent transcatheter closure of PDA at our institution between 20th January 2006 and 27th June 2008 were retrospectively identified and studied. There were a total of 66 patients who had undergone transcatheter closure of PDA during this period which comprised of 24 male and 42 female. The PDA was closed by Amplatzer Duct Occluder (ADO) in 31 patients, Gianturco coil in 29 patients and other types of devices in 6 patients. There were 4 patients (6%) who had developed acute complication during the procedure (3 of them developed coil embolization and 1 had bleeding from puncture site). The PDA was successfully close in 95.5% of the study population without any residual PDA shunting. All the patients were alive but 5 of them (4.5%) have some abnormalities (2 has mild left pulmonary stenosis, 3 has small residual). Comparison between ADO and Gianturco coil revealed no significant difference in the outcome. Transcatheter closure of PDA has proven to be safe and effective with good midterm outcome. There was no significant difference between Amplatzer Ductal Occluder and Gianturco coil in term of the outcome.

摘要

经导管闭合中小尺寸动脉导管未闭(PDA)是一种标准且被广泛接受的治疗方式。本研究旨在描述槟城医院经导管闭合PDA的经验。回顾性确定并研究了2006年1月20日至2008年6月27日期间在我院接受经导管闭合PDA的所有患者。在此期间共有66例患者接受了经导管闭合PDA,其中男性24例,女性42例。31例患者使用Amplatzer动脉导管封堵器(ADO)闭合PDA,29例患者使用Gianturco弹簧圈,6例患者使用其他类型的器械。4例患者(6%)在手术过程中出现急性并发症(其中3例发生弹簧圈栓塞,1例穿刺部位出血)。95.5%的研究人群中PDA成功闭合,无残余PDA分流。所有患者均存活,但其中5例(4.5%)有一些异常情况(2例有轻度左肺动脉狭窄,3例有小的残余分流)。ADO与Gianturco弹簧圈之间的比较显示结果无显著差异。经导管闭合PDA已被证明是安全有效的,中期结果良好。Amplatzer动脉导管封堵器与Gianturco弹簧圈在结果方面无显著差异。

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