多刺激响应性高分子及其组装体。
Multi-stimuli responsive macromolecules and their assemblies.
机构信息
Department of Chemistry, University of Massachusetts, Amherst, MA 01003, USA.
出版信息
Chem Soc Rev. 2013 Sep 7;42(17):7421-35. doi: 10.1039/c3cs60094g. Epub 2013 Jun 13.
Abstract
In this review, we outline examples that illustrate the design criteria for achieving macromolecular assemblies that incorporate a combination of two or more chemical, physical or biological stimuli-responsive components. Progress in both fundamental investigation into the phase transformations of these polymers in response to multiple stimuli and their utilization in a variety of practical applications are highlighted. Using these examples, we aim to explain the origin of employed mechanisms of stimuli responsiveness which may serve as a guideline to inspire future design of multi-stimuli responsive materials.
摘要
在这篇综述中，我们概述了一些例子，说明了实现包含两种或多种化学、物理或生物刺激响应组件的大分子组装体的设计标准。强调了这些聚合物对多种刺激的相转变的基础研究进展及其在各种实际应用中的利用。通过这些例子，我们旨在解释所采用的刺激响应机制的起源，这些机制可以作为启发未来多刺激响应材料设计的指南。
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ACS Macro Lett. 2012 May 15;1(5):632-635. doi: 10.1021/mz300135x. Epub 2012 Apr 24.
2
pH-Responsive polymers: synthesis, properties and applications.pH响应性聚合物：合成、性质及应用
Soft Matter. 2008 Feb 21;4(3):435-449. doi: 10.1039/b714741d.
3
Designing two self-assembly mechanisms into one viral capsid protein.设计两种自组装机制于一种病毒衣壳蛋白。
J Am Chem Soc. 2012 Nov 14;134(45):18506-9. doi: 10.1021/ja308132z. Epub 2012 Nov 1.
4
Dual environment-responsive polyplex carriers for enhanced intracellular delivery of plasmid DNA.双环境响应性聚合物载体用于增强质粒 DNA 的细胞内递送。
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