BC Children's Hospital, Department of Pediatrics, Room K4-226, Ambulatory Care Bldg, 4480 Oak St, Vancouver, BC V6H 3V4, Canada.
Can Fam Physician. 2013 Jun;59(6):635-6.
In my office I occasionally see children who have rashes with "target lesions" and who are diagnosed with erythema multiforme (EM). When should these children receive steroids, and when should the illness be allowed to follow its natural course without steroid treatment?
Erythema multiforme is relatively common in children. Current recommendations suggest not to treat EM minor with systemic steroids and that topical steroids might be of benefit. The use of systemic steroids for EM major remains controversial, as there is evidence both for and against treatment, and no randomized controlled trials have been done. Further studies need to address the benefit of steroids, and in the interim, physicians should decide on a treatment based on the severity of EM and in consultation with a dermatologist, if available.
在我的诊所，我偶尔会看到患有“靶形皮损”的皮疹儿童，并被诊断为多形性红斑（EM）。这些孩子何时应该接受类固醇治疗，何时应该让疾病在没有类固醇治疗的情况下自然发展？
多形性红斑在儿童中较为常见。目前的建议是，对于 EM 轻症不采用全身性类固醇治疗，而局部类固醇可能有益。对于 EM 重症，使用全身性类固醇仍然存在争议，因为有支持和反对治疗的证据，而且没有进行随机对照试验。需要进一步的研究来确定类固醇的疗效，在此期间，医生应根据 EM 的严重程度并在有皮肤科医生咨询的情况下决定治疗方案。
