Shono T, Scott J G
Department of Entomology, Cornell University, Ithaca, New York 14853.
J Econ Entomol. 1990 Jun;83(3):686-9. doi: 10.1093/jee/83.3.686.
Mechanisms and genetics of resistance to pyrethroid insecticides were investigated in a strain of house fly (ASPR) collected from a cattle ranch in Miyagi, Gunma Prefecture, Japan. Flies were selected in the laboratory with the pyrethroid insecticide permethrin. Both sexes were resistant to pyrethroids; however, females were 22- to 245-fold more resistant than males. Permethrin resistance could be partly suppressed by the monooxygenase inhibitor piperonyl butoxide in females, but not in males. In this strain, sex was determined by a male factor on the third autosome. The relationship of the autosomal male factor to the lower resistance levels observed in the males and the mechanisms of resistance expressed in each sex are discussed.
在从日本群马县宫城县一个养牛场采集的家蝇品系（ASPR）中，研究了对拟除虫菊酯类杀虫剂的抗性机制和遗传学。在实验室中用拟除虫菊酯类杀虫剂氯菊酯对家蝇进行筛选。雌雄两性均对拟除虫菊酯具有抗性；然而，雌性的抗性比雄性高22至245倍。雌性家蝇中，单加氧酶抑制剂胡椒基丁醚可部分抑制氯菊酯抗性，但雄性家蝇中则不能。在这个品系中，性别由第三条常染色体上的雄性因子决定。讨论了常染色体雄性因子与雄性较低抗性水平之间的关系以及两性中表达的抗性机制。
