Mittal S R
Department of Cardiology, St. Francis Hospital, Beawar Road, Ajmer, Rajasthan.
J Assoc Physicians India. 2012 Nov;60:16-21.
There is only scanty data on tissue Doppler imaging (TDI) of 'normal' adults.
Twenty eight asymptomatic adults (20-45 yrs) without cardiovascular risk factors, clinic BP < or = 120/80mmHg and normal echocardiographic examination were evaluated by tissue Doppler imaging to find normal reference values in this population.
There was significant heterogeneity in TDI velocities and duration of different segments of left ventricle (LV). Sa and Ea velocities were lower at medial mitral annulus and middle part of interventricular septum (IVS) than at lateral mitral annulus and middle part of left ventricular lateral wall. Isovolumic contraction time (IVCT) was significantly less at lateral mitral annulus and mid part of lateral wall of LV. Isovolumic relaxation time (IVRT) was significantly less at lateral mitral annulus. Aa velocity was lower at middle part of IVS. E/Ea velocity ratio was significantly lower at lateral mitral annulus. Ea/Aa velocity ratio was always more than 1. Relatively higher values were recorded at lateral mitral annulus and mid part of left lateral wall. Myocardial performance index values were higher at mid segments than at annulus.
Our data provides reference values of TDI for healthy normal adults and may help in the detection of onset of early diastolic dysfunction in this age group.
关于“正常”成年人的组织多普勒成像（TDI）的数据非常有限。
对28名无心血管危险因素、临床血压≤120/80mmHg且超声心动图检查正常的无症状成年人（20 - 45岁）进行组织多普勒成像评估，以确定该人群的正常参考值。
左心室（LV）不同节段的TDI速度和持续时间存在显著异质性。二尖瓣内侧环和室间隔中部（IVS）的Sa和Ea速度低于二尖瓣外侧环和左心室侧壁中部。二尖瓣外侧环和左心室侧壁中部的等容收缩时间（IVCT）显著缩短。二尖瓣外侧环的等容舒张时间（IVRT）显著缩短。IVS中部的Aa速度较低。二尖瓣外侧环的E/Ea速度比值显著较低。Ea/Aa速度比值始终大于1。二尖瓣外侧环和左心室侧壁中部记录到相对较高的值。心肌做功指数值在节段中部高于瓣环处。
我们的数据提供了健康正常成年人的TDI参考值，可能有助于检测该年龄组早期舒张功能障碍的发病情况。
