Department of Chemistry, University of Washington, Seattle, Washington 98195-17000, USA.
Anal Chem. 2013 Jul 2;85(13):6190-4. doi: 10.1021/ac400844p. Epub 2013 Jun 14.
This Letter describes the controlled generation of double emulsions in the gas phase, which was carried out using an integrated emitter in a poly(dimethylsiloxane) (PDMS) microfluidic chip. The integrated emitter was formed using a molding approach, in which metal wires with desirable diameters were used as emitter molds. The generation of double emulsions in air was achieved with electrohydrodynamics actuation, which offers controllable force exerting on the double emulsions. We developed this capability for future integration of droplet microfluidics with mass spectrometry (MS), where each aqueous droplet in the microchannel is introduced into the gas phase as a double emulsion for subsequent ionization and MS analysis.
这封信描述了在气相中控制生成双重乳液的过程，该过程使用聚二甲基硅氧烷 (PDMS) 微流控芯片中的集成式喷口完成。集成式喷口通过注塑成型的方法形成，该方法使用具有所需直径的金属丝作为喷口模具。通过电动力学致动实现了在空气中生成双重乳液，该方法可对双重乳液施加可控的力。我们开发了这种功能，以便将来将液滴微流控技术与质谱 (MS) 进行集成，在微通道中，每个水性液滴都作为双重乳液引入气相，以便随后进行离子化和 MS 分析。
