细菌，是今晚的主菜。

Bacteria, it's what's for dinner.

机构信息

Kimmel Center for Biology and Medicine at the Skirball Institute, Department of Microbiology, New York University School of Medicine, New York, NY 10016, USA.

出版信息

Cell Host Microbe. 2013 Jun 12;13(6):627-8. doi: 10.1016/j.chom.2013.05.011.

DOI:10.1016/j.chom.2013.05.011

PMID:23768486

Abstract

While intestinal epithelial cells are known for secreting antimicrobial molecules, cell intrinsic defense mechanisms are less characterized. In this issue, Benjamin et al. (2013) demonstrate that MyD88 and autophagy within the intestinal epithelium detect invasive bacteria and prevent dissemination.

摘要

虽然肠上皮细胞以分泌抗菌分子而闻名，但细胞内在的防御机制却鲜为人知。在本期杂志中，Benjamin 等人（2013 年）证明了肠上皮细胞中的 MyD88 和自噬可以检测到入侵的细菌并防止其扩散。