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对斯蒂尔病相关硬脑膜炎症性假瘤中类固醇治疗的完全反应。

Complete response to steroids in dural inflammatory pseudotumor associated with Still's disease.

机构信息

Duke Brain Tumor Immunotherapy Program, Duke University Medical Center, Durham, NC, USA; Department of Pathology, Duke University Medical Center, Durham, NC, USA.

出版信息

J Clin Neurosci. 2013 Oct;20(10):1445-8. doi: 10.1016/j.jocn.2013.01.009. Epub 2013 Jun 12.

Abstract

We report a unique case of a dural-based inflammatory pseudotumor (IPT) arising in the left cavernous sinus of a patient with a history of juvenile Still's disease. The patient presented with hemi-facial paresthesias, dull, constant headaches, and transient episodes of sharp pain along the temporalis region. Treatment with oral steroid therapy resulted in complete regression of the lesion and accompanied neuralgia symptoms. Because intracranial IPT can mimic meningiomas both clinically and radiographically and can be associated with systemic arthritic diseases, neurosurgeons should be familiar with this entity in order to avoid unnecessary radical surgery and alternatively consider a tapering course of steroid therapy.

摘要

我们报告了一例独特的病例,一名患有幼年Still 病病史的患者左侧海绵窦内出现基于硬脑膜的炎症性假瘤(IPT)。该患者表现为半侧面部感觉异常、钝痛、持续性头痛,并伴有颞区短暂的锐痛。口服类固醇治疗导致病变完全消退,并伴有神经痛症状。由于颅内 IPT 在临床和影像学上可模拟脑膜瘤,并可与全身关节炎性疾病相关,神经外科医生应熟悉这一实体,以避免不必要的根治性手术,并考虑采用类固醇逐渐减量的治疗方案。

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