The role of FDG-PET in the interim evaluation of therapy response in diffuse large B-cell lymphoma.

The significance of FDG PET in the interim follow-up of patients with diffuse large B-cell lymphoma to evaluate therapy response is currently being debated. Reports with discordant results have been published. Several authors have reported a low positive predictive value when using FDG PET to evaluate interim therapy response. Different criteria for the interpretation of PET studies in these patients are available, producing variable results. The latest publications and the review criteria will be summarised in this paper.