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氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)在弥漫性大B细胞淋巴瘤治疗反应中期评估中的作用

The role of FDG-PET in the interim evaluation of therapy response in diffuse large B-cell lymphoma.

作者信息

Ellmann Annare

机构信息

Nuclear Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.

出版信息

Transfus Apher Sci. 2013 Aug;49(1):40-2. doi: 10.1016/j.transci.2013.05.023. Epub 2013 Jun 14.

DOI:10.1016/j.transci.2013.05.023
PMID:23769694
Abstract

The significance of FDG PET in the interim follow-up of patients with diffuse large B-cell lymphoma to evaluate therapy response is currently being debated. Reports with discordant results have been published. Several authors have reported a low positive predictive value when using FDG PET to evaluate interim therapy response. Different criteria for the interpretation of PET studies in these patients are available, producing variable results. The latest publications and the review criteria will be summarised in this paper.

摘要

18F-氟代脱氧葡萄糖正电子发射断层扫描(FDG PET)在弥漫性大B细胞淋巴瘤患者中期随访中评估治疗反应的意义目前仍存在争议。已有结果不一致的报告发表。几位作者报告称,使用FDG PET评估中期治疗反应时阳性预测值较低。对于这些患者,PET研究解读的标准各不相同,结果也存在差异。本文将总结最新的出版物及评估标准。

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