Centre of Physics, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal; Centre of Chemistry, University of Minho, Campus of Gualtar, 4710-057 Braga, Portugal.
Ultrason Sonochem. 2014 Jan;21(1):360-6. doi: 10.1016/j.ultsonch.2013.05.010. Epub 2013 May 29.
Ultrasound irradiation was used for the first time towards the synthesis of new Nile Blue related benzo[a]phenoxazinium chlorides possessing isopentylamino, (2-cyclohexylethyl)amino and phenethylamino groups at 5-position of the heterocyclic system. The efficacy of sonochemistry was investigated with some of our earlier reported synthesis of benzo[a]phenoxazinium chlorides. This newer protocol proved competent in terms of reaction times and enhanced yields. Photophysical studies carried out in ethanol, water and simulated physiological conditions, revealed that emission maxima occurred in the range 644-656 nm, with high fluorescent quantum yields. Other attractive feature exhibited by these materials includes good thermal stability. These properties might be useful in the development of fluorescent probes for biotechnology.
超声辐射首次用于合成新的尼罗蓝相关苯并[a]吩恶嗪鎓氯化物，这些化合物在杂环系统的 5 位具有异戊基氨基、（2-环己基乙基）氨基和苯乙氨基。超声化学的功效通过我们之前报道的一些苯并[a]吩恶嗪鎓氯化物的合成进行了研究。与我们之前报道的一些合成方法相比，这个新的方案在反应时间和产率方面都有优势。在乙醇、水和模拟生理条件下进行的光物理研究表明，发射最大值出现在 644-656nm 范围内，具有高荧光量子产率。这些材料表现出的其他吸引人的特性包括良好的热稳定性。这些性质可能对生物技术中荧光探针的开发有用。
