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源自顶叶皮质发育异常的痴笑发作和发热

Gelastic seizures and fever originating from a parietal cortical dysplasia.

作者信息

Chaouki Sana, Boujraf Saïd, Atmani Samir, Elarqam Larbi, Messouak Wafae

机构信息

Department of Pediatrics, University Hospital of Fez, Morocco.

出版信息

J Pediatr Neurosci. 2013 Jan;8(1):70-2. doi: 10.4103/1817-1745.111433.

Abstract

Gelastic seizures (GS) is an uncommon seizure type characterized by sudden inappropriate attacks of uncontrolled and unmotivated laugh and its diagnostic criteria were elaborated by Gascon. These criteria included stereotypical recurrence of laugh, which is unjustified by the context, associated signs compatible with seizure, and ictal or interictal abnormalities. GS can be cryptogenic or symptomatic of a variety of cerebral lesions, the most common being hypothalamic hamartoma. However, GS associated with other types of cerebral lesions are exceedingly rare. The physiopathologic mechanisms of this type of seizure are still undefined. Two reports have described a non-lesional GS arising from a parietal focus. In this paper, we report the first case of lesional GS associated to the parietal area of the brain in a child and this case has associated fever that is likely an ictal symptom.

摘要

痴笑性癫痫(GS)是一种不常见的癫痫发作类型,其特征为突然出现无法控制且无动机的不适当发笑发作,其诊断标准由加斯孔阐述。这些标准包括刻板性发笑复发,在当时情境下无正当理由,伴有与癫痫发作相符的体征,以及发作期或发作间期异常。GS可为隐源性或由多种脑病变引起,最常见的是下丘脑错构瘤。然而,与其他类型脑病变相关的GS极为罕见。这种癫痫发作类型的生理病理机制仍不明确。有两份报告描述了源于顶叶病灶的非病变性GS。在本文中,我们报告了首例儿童大脑顶叶区域相关的病变性GS病例,且该病例伴有发热,发热可能是一种发作期症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4373/3680904/5e7768e0b583/JPN-8-70-g001.jpg

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