Suppr超能文献

单一机构25年背根入髓区毁损术的经验。

Experience with 25 years of dorsal root entry zone lesioning at a single institution.

作者信息

Awad Ahmed J, Forbes Jonathan A, Jermakowicz Walter, Eli Ilyas M, Blumenkopf Bennett, Konrad Peter

机构信息

Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

出版信息

Surg Neurol Int. 2013 May 17;4:64. doi: 10.4103/2152-7806.112182. Print 2013.

Abstract

BACKGROUND

The authors sought to assess long-term efficacy, surgical morbidity, and postoperative quality of life in patients who have undergone dorsal root entry zone (DREZ) lesioning.

METHODS

We utilized the electronic chart system at our institution to identify patients who underwent DREZ lesioning since 1986. Of the patients that were able to be identified, 19 (12 males and 7 females) patients were able to be contacted at time of data collection. The mean age was 47 years (ranging from 23 to 70 years) with average preoperative pain duration of 12.5 years and average follow-up of 4.9 years.

RESULTS

Of the 19 patients we were able to contact, 7 (37%) patients experienced "excellent" postoperative (complete) pain relief with another 6 (32%) reporting "good" improvement. Three (16%) patients reported "mild" pain relief, while three (16%) patients reported poor results. Sixteen patients (84%) stated they would undergo DREZ lesioning again, if given a choice. Two patients (11%) had objective evidence of a new, mild motor deficit postoperatively. More than half of the patients, who answered, reported "good" quality of life. Two-sample unequal variance t-test showed no statistically significant difference in pain improvement between brachial plexus avulsion and end-zone spinal cord injury pain.

CONCLUSION

With appropriate patient selection, DREZ lesioning is an efficacious and durable procedure that can be performed with low morbidity and good patient outcomes.

摘要

背景

作者试图评估接受背根入髓区(DREZ)毁损术患者的长期疗效、手术并发症及术后生活质量。

方法

我们利用本机构的电子病历系统,识别自1986年以来接受DREZ毁损术的患者。在能够识别的患者中,19例(12例男性和7例女性)患者在数据收集时能够取得联系。平均年龄为47岁(范围从23岁至70岁),术前平均疼痛持续时间为12.5年,平均随访时间为4.9年。

结果

在我们能够联系到的19例患者中,7例(37%)患者术后疼痛得到“极佳”(完全)缓解,另外6例(32%)报告有“良好”改善。3例(16%)患者报告有“轻度”疼痛缓解,而3例(16%)患者报告效果不佳。16例患者(84%)表示,如果可以选择,他们会再次接受DREZ毁损术。2例患者(11%)术后有新的轻度运动功能障碍的客观证据。超过一半做出回答的患者报告生活质量“良好”。两样本异方差t检验显示,臂丛神经撕脱伤和终末区脊髓损伤疼痛在疼痛改善方面无统计学显著差异。

结论

通过适当选择患者,DREZ毁损术是一种有效且持久的手术,可在低并发症发生率和良好患者预后的情况下进行。

相似文献

1
Experience with 25 years of dorsal root entry zone lesioning at a single institution.
Surg Neurol Int. 2013 May 17;4:64. doi: 10.4103/2152-7806.112182. Print 2013.
3
Dorsal Root Entry Zone Lesioning for the Treatment of Pain After Brachial Plexus Avulsion Injury: 2-Dimensional Operative Video and Technical Report.
Oper Neurosurg (Hagerstown). 2022 Jun 1;22(6):e252-e258. doi: 10.1227/ons.0000000000000149. Epub 2022 Apr 14.
4
Modified dorsal root entry zone lesioning for intractable pain relief in patients with root avulsion injury.
J Neurosurg Spine. 2017 Aug;27(2):178-184. doi: 10.3171/2017.1.SPINE16234. Epub 2017 Jun 2.
5
Dorsal Root Entry Zone Lesioning Following Unresponsive Spinal Cord Stimulation for Post-Traumatic Neuropathic Pain.
World Neurosurg. 2023 Oct;178:e300-e306. doi: 10.1016/j.wneu.2023.07.048. Epub 2023 Jul 18.
6
Is dorsal root entry zone lesioning effective and safe for managing continuous versus paroxysmal pains post-brachial plexus avulsion?
J Neurosurg Spine. 2023 Mar 31;39(1):101-112. doi: 10.3171/2023.2.SPINE221252. Print 2023 Jul 1.
7
Dorsal root entry zone lesioning for brachial plexus avulsion - technical evolution and long-term follow-up.
Acta Neurochir (Wien). 2024 May 30;166(1):241. doi: 10.1007/s00701-024-06132-9.
8
Spinal and Nucleus Caudalis Dorsal Root Entry Zone Lesioning for Chronic Pain: Efficacy and Outcomes.
World Neurosurg. 2015 Aug;84(2):494-504. doi: 10.1016/j.wneu.2015.04.025. Epub 2015 Apr 18.
9
Retrospective Study of 57 Patients Submitted to Dorsal Root Entry Zone Lesioning by Radiofrequency for Brachial Plexus Avulsion Pain.
World Neurosurg. 2023 Sep;177:e466-e471. doi: 10.1016/j.wneu.2023.06.077. Epub 2023 Jun 24.
10
Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion: A Comprehensive Literature Review.
Oper Neurosurg (Hagerstown). 2021 Mar 15;20(4):324-333. doi: 10.1093/ons/opaa447.

引用本文的文献

2
Dorsal root entry zone lesioning for brachial plexus avulsion - technical evolution and long-term follow-up.
Acta Neurochir (Wien). 2024 May 30;166(1):241. doi: 10.1007/s00701-024-06132-9.
3
Dorsal root entry zone lesioning for brachial plexus avulsion pain: a case series.
Spinal Cord Ser Cases. 2023 Mar 9;9(1):6. doi: 10.1038/s41394-023-00564-8.
4
Dorsal Root Entry Zone Lesioning for Brachial Plexus Avulsion Injuries: Case Series and Literature Review.
Front Pain Res (Lausanne). 2021 Nov 17;2:749801. doi: 10.3389/fpain.2021.749801. eCollection 2021.
5
Chemogenetics: Beyond Lesions and Electrodes.
Neurosurgery. 2021 Jul 15;89(2):185-195. doi: 10.1093/neuros/nyab147.

本文引用的文献

1
Post herpetic neuralgia.
J Palliat Med. 2011 Jun;14(6):765-73. doi: 10.1089/jpm.2011.9685.
2
21. Phantom pain.
Pain Pract. 2011 Jul-Aug;11(4):403-13. doi: 10.1111/j.1533-2500.2011.00454.x. Epub 2011 Mar 30.
3
[A study on neurosurgical treatment for phantom limb pain].
Zhonghua Wai Ke Za Zhi. 2007 Dec 15;45(24):1668-71.
4
Spinal and nucleus caudalis dorsal root entry zone operations for chronic pain.
Neurosurgery. 2008 Mar;62(3 Suppl 1):235-42; discussion 242-4. doi: 10.1227/01.neu.0000317398.93218.e0.
5
Neuropathic pain: redefinition and a grading system for clinical and research purposes.
Neurology. 2008 Apr 29;70(18):1630-5. doi: 10.1212/01.wnl.0000282763.29778.59. Epub 2007 Nov 14.
8
Opioids in neuropathic pain.
Curr Pharm Des. 2005;11(23):3013-25. doi: 10.2174/1381612054865055.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验