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[中枢灰质与黑质联合刺激对麻醉大鼠低阈值和高阈值惊跳反射的影响]

[The effect of the joint stimulation of the central grey substance and substantia nigra on the low- and high-threshold startle reflexes in anesthetized rats].

作者信息

Karpukhina M V, Gokin A P

出版信息

Neirofiziologiia. 1990;22(2):276-9.

PMID:2377258
Abstract

Influences of separate and combined stimulation of the periaqueductal grey matter (PAG) and the substantia nigra (SN) on startle reflexes were studied in chloralose-anesthetized rats; the reflexes were low-threshold, tactile ones and high-threshold, spino-bulbo-spinal (SBS) ones. A clear interaction between effects of the PAG and SN stimuli occurred by combination of these stimulations was found. The interactions were exhibited with potentiation or diminution of influences evoked by separate stimuli depending on type of reflexes investigated and sorts of influences as well as on sequences of stimulations. Potentiation of the inhibitory action of PAG stimulation on the SBS-reflex by combination of PAG-SN was observed more often.

摘要

在水合氯醛麻醉的大鼠中,研究了中脑导水管周围灰质(PAG)和黑质(SN)单独及联合刺激对惊跳反射的影响;这些反射包括低阈值触觉反射和高阈值脊髓-延髓-脊髓(SBS)反射。发现通过联合刺激,PAG和SN刺激的效应之间存在明显的相互作用。根据所研究的反射类型、影响种类以及刺激顺序,这些相互作用表现为单独刺激所诱发的影响的增强或减弱。PAG-SN联合刺激更常观察到增强PAG刺激对SBS反射的抑制作用。

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