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[意义不明的周期性嗜酸性粒细胞增多伴获得性特发性铁粒幼细胞贫血。病例报告]

[Acquired idiopathic sideroblastic anemia with cyclic hypereosinophilia of unclear significance. A case report].

作者信息

D'Angelo G, Mattaini R, Cosini I, Zanco M D

机构信息

Presidio Ospedaliero di Somma Lombardo, U.S.S.L. n. 6, Gallarate (Varese).

出版信息

Minerva Med. 1990 May;81(5):433-7.

PMID:2377310
Abstract

We considered the case of an eighty-three-years-old woman who was admitted to Somma Lombardo Hospital, because of the presence of an acquired sideroblastic idiopathic anaemia accompanied by a cyclic hypereosinophilia of undefined significance. The case is reported both because references about sideroblastic idiopathic anaemia with hypereosinophilia of undefined significance are rare in the literature and because it may support the hypothesis that hypereosinophilia ensues from the myelodysplastic syndrome. Therefore it is possible that when diagnosing acquired sideroblastic idiopathic anaemia, not only thrombocytopenia, but hypereosinophilia has to be considered as an unfavourable prognostic marker for early appearance of acute non-lymphoid leukemia.

摘要

我们考虑了一位83岁女性的病例,她因患有获得性特发性铁粒幼细胞贫血并伴有意义未明的周期性嗜酸性粒细胞增多症而入住索马伦巴多医院。报告该病例的原因,一是关于意义未明的嗜酸性粒细胞增多症合并特发性铁粒幼细胞贫血的文献报道很少,二是该病例可能支持嗜酸性粒细胞增多症由骨髓增生异常综合征引起的假说。因此,在诊断获得性特发性铁粒幼细胞贫血时,不仅血小板减少,而且嗜酸性粒细胞增多也应被视为急性非淋巴细胞白血病早期出现的不良预后指标。

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