英国肾脏注册中心第 15 份年度报告：第 2 章 2011 年英国 RRT 的患病率：全国和中心特异性分析。

UK Renal Registry 15th annual report: Chapter 2 UK RRT prevalence in 2011: national and centre-speciﬁc analyses.

机构信息

UK Renal Registry, Bristol, UK.

出版信息

Nephron Clin Pract. 2013;123 Suppl 1:29-54. doi: 10.1159/000353321. Epub 2013 Jun 10.

DOI:10.1159/000353321

PMID:23774485

Abstract

INTRODUCTION

This chapter describes the characteristics of adult patients on renal replacement therapy (RRT) in the UK in 2011. The prevalence rates per million population (pmp) were calculated for Primary Care Trusts in England, Health and Social Care areas in Northern Ireland, Local Health Boards in Wales and Health Boards (HB) in Scotland (PCT/HB areas).

METHODS

Data were electronically collected from all 71 renal centres within the UK. A series of cross-sectional and longitudinal analyses were performed to describe the demographics of prevalent RRT patients in 2011 at centre and national level. Age and gender standardised ratios for prevalence rates in PCT/ HBs were calculated.

RESULTS

There were 53,207 adult patients receiving RRT in the UK on 31st December 2011. The UK adult prevalence of RRT was 842 pmp. This represented an annual increase in prevalent numbers of approximately 4%, although there was variation between centres and PCT/HB areas. The growth rate from 2010 to 2011 for prevalent patients by treatment modality in the UK was an increase of 1.7% for haemodialysis (HD), a fall of 2.2% for peritoneal dialysis (PD) and an increase of 4.7% with a functioning transplant. There has been a slow but steady decline in the proportion of dialysis patients receiving PD since 2000. In contrast, the number of patients receiving home HD has increased 16% since 2010. Median RRT vintage for patients on HD was 3.3 years, PD 1.8 years and for those patients with a transplant, 10.3 years. The median age of prevalent patients was 58.2 years (HD 66.5 years, PD 62.7 years, transplant 51.7 years) compared to 55 years in 2000. For all ages the prevalence rate in men exceeded that in women, peaking in age group 75-79 years at 2,918 pmp in males. For females the peak was in age group 65-69 years at 1,460 pmp. The most common recorded renal diagnosis was glomerulonephritis (biopsy proven/not biopsy proven) (19%), followed by uncertain (18%). Transplantation was the most common treatment modality (48.6%), HD in 43.9% and PD 7.6%. However, HD was increasingly common with increasing age and transplantation less common.

CONCLUSIONS

The HD and transplant population continued to expand whilst the PD population contracted. There were national, regional and dialysis centre level variations in prevalence rates. Prevalent patients were on average three years older than 10 years ago. This has implications for service planning and ensuring equity of care for RRT patients.

摘要

简介

本章描述了 2011 年英国接受肾脏替代治疗（RRT）的成年患者的特征。百万人口患病率（pmp）在英格兰的初级保健信托、北爱尔兰的卫生和社会保健区、威尔士的地方卫生委员会和苏格兰的卫生委员会（PCT/HB 区）中进行了计算。

方法

从英国所有 71 个肾脏中心电子收集数据。对中心和国家层面 2011 年 RRT 患者的流行率进行了一系列横断面和纵向分析。计算了按 PCT/HB 区计算的年龄和性别标准化患病率比值。

结果

2011 年 12 月 31 日，英国有 53207 名成年患者接受 RRT。英国成年人 RRT 的患病率为 842 pmp。这代表着流行人数每年约增长 4%，尽管中心和 PCT/HB 区之间存在差异。从 2010 年到 2011 年，英国按治疗方式分类的流行患者增长率为血液透析（HD）增加 1.7%，腹膜透析（PD）减少 2.2%，功能移植增加 4.7%。自 2000 年以来，接受 PD 治疗的透析患者比例一直在缓慢但稳步下降。相比之下，自 2010 年以来，接受家庭血液透析的患者人数增加了 16%。接受 HD 治疗的患者的中位 RRT 年限为 3.3 年，PD 为 1.8 年，接受移植的患者为 10.3 年。HD 患者的中位年龄为 58.2 岁（HD 为 66.5 岁，PD 为 62.7 岁，移植为 51.7 岁），而 2000 年为 55 岁。在所有年龄段中，男性的患病率均高于女性，75-79 岁年龄组的男性患病率最高，为 2918 pmp。女性的患病率高峰出现在 65-69 岁年龄组，为 1460 pmp。最常见的记录肾脏诊断是肾小球肾炎（活检证实/未活检证实）（19%），其次是不确定（18%）。移植是最常见的治疗方式（48.6%），HD 为 43.9%，PD 为 7.6%。然而，随着年龄的增长，HD 越来越普遍，而移植则越来越少。