UK Renal Registry, Southmead Hospital, Bristol, UK.
Nephron Clin Pract. 2011;119 Suppl 2:c1-25. doi: 10.1159/000331741. Epub 2011 Aug 26.
This chapter describes the characteristics of adult patients starting renal replacement therapy (RRT) in the UK in 2009 and the acceptance rates for RRT in Primary Care Trusts and Health Boards (PCT/HBs) in the UK.
The basic demographics and clinical characteristics are reported on patients starting RRT from all UK renal centres. Late presentation, defined as time between first being seen by a nephrologist and start of RRT being <90 days was also studied. Age and gender standardised ratios for acceptance rates in PCT/HBs were calculated.
In 2009, the incidence rate in the UK and England was 109 per million population (pmp). Acceptance rates in Scotland (104 pmp), Northern Ireland (88 pmp) and Wales (120 pmp) had all fallen although Wales still remained the country with the highest acceptance rate. There were wide variations between PCT/HBs with respect to the standardised ratios. The median age of all incident patients was 64.8 years (IQR 50.8, 75.1). For transplant centres this was 63.0 years (IQR 49.0, 74.2) and for non-transplanting centres 66.3 years (IQR 52.6, 75.9). The median age for non-Whites was 57.1 years. Diabetic renal disease remained the single most common cause of renal failure (25%). By 90 days, 69.1% of patients were on haemodialysis, 17.7% on peritoneal dialysis, 6.7% had had a transplant and 6.5% had died or stopped treatment. The mean eGFR at the start of RRT was 8.6 ml/min/1.73 m2 which was similar to the previous two years. Late presentation (<90 days) has fallen from 27% in 2004 to 19% in 2009. There was no relationship between social deprivation and presentation pattern.
Acceptance rates have fallen in Northern Ireland, Scotland and Wales whilst they have plateaued in England over the last four years. Wales continued to have the highest acceptance rate of the countries making up the UK.
本章描述了 2009 年英国开始接受肾脏替代治疗(RRT)的成年患者的特征,以及英国初级保健信托和卫生委员会(PCT/HBs)接受 RRT 的比率。
报告了所有英国肾脏中心开始接受 RRT 的患者的基本人口统计学和临床特征。还研究了延迟就诊的情况,定义为首次接受肾病学家就诊和开始 RRT 的时间<90 天。计算了 PCT/HBs 中接受率的年龄和性别标准化比值。
2009 年,英国和英格兰的发病率为每百万人口 109 例(pmp)。苏格兰(104 pmp)、北爱尔兰(88 pmp)和威尔士(120 pmp)的接受率均有所下降,尽管威尔士的接受率仍然最高。PCT/HBs 之间存在广泛的差异。所有新发病例患者的中位年龄为 64.8 岁(IQR 50.8,75.1)。对于移植中心,这一年龄为 63.0 岁(IQR 49.0,74.2),而非移植中心为 66.3 岁(IQR 52.6,75.9)。非白人的中位年龄为 57.1 岁。糖尿病肾病仍然是肾衰竭的最常见原因(25%)。90 天后,69.1%的患者接受血液透析,17.7%接受腹膜透析,6.7%接受了移植,6.5%死亡或停止治疗。开始 RRT 时的平均 eGFR 为 8.6 ml/min/1.73 m2,与前两年相似。延迟就诊(<90 天)从 2004 年的 27%下降到 2009 年的 19%。社会贫困程度与就诊模式之间没有关系。
过去四年,北爱尔兰、苏格兰和威尔士的接受率有所下降,而英格兰的接受率则趋于平稳。威尔士继续保持着英国各组成国家中最高的接受率。