Iwahashi Aya, Nakatani Yasuki, Hirobata Tomonao, Nakata Hirosuke, Funakoshi Shogo, Yamashita Yukitaka, Inoue Gen
Department of Diabetes and Endocrinology, Wakayama Medical Center Japanese Red Cross Society, Japan.
Intern Med. 2013;52(12):1375-8. doi: 10.2169/internalmedicine.52.8796.
A 42-year-old woman with a history of idiopathic portal hypertension (IPH) developed type 1A diabetes and was found to have chronic thyroiditis. The concurrence of IPH and type 1A diabetes has been previously reported in only one case. This is the second known case, and our patient was classified as having autoimmune polyglandular syndrome (APS) III. The patient's HLA DR and DQ alleles were determined to be susceptible to autoimmune thyroid diseases but resistant to type 1A diabetes.
一名有特发性门静脉高压（IPH）病史的42岁女性患1A型糖尿病，并被发现患有慢性甲状腺炎。IPH和1A型糖尿病并发此前仅在1例中报道过。这是已知的第2例，我们的患者被归类为患有自身免疫性多腺体综合征（APS）III型。患者的HLA DR和DQ等位基因被确定易患自身免疫性甲状腺疾病，但对1A型糖尿病有抗性。
