Alt E, Matula M, Theres H, Thilo R
I. Medizinische Klinik, Klinikum rechts der Isar, TU München.
Z Kardiol. 1990 Jun;79(6):408-16.
In the past, the most important feature in the development of rate-responsive pacemaker systems was ensuring an adequate rate response to physical exercise. But there are other variables that modulate the rate of the healthy heart; examples include postural changes in heart rate in order to prevent orthostatic reactions, and the nightly decrease in intrinsic pacemaker rate. Therefore, we developed a sensor that could distinguish, not only rest and activity, but also discriminate between a supine and an upright position. This sensor is a multicontact tilt switch, which contains a small mercury ball. By measuring the number of openings and closures within the sensor as the ball touches the numerous sensor contacts it is possible to discriminate between different levels of exercise; the contact pins are circled around the base plate. There is an almost linear increase in the number of changes per time with increasing exercise. Besides measuring body activity from the number of contact changes per time, it is also possible to determine the body's posture from the count and positioning of the closed contacts within the casing. Based upon the results of 12 volunteers and nine pacemaker patients, a new algorithm is being prepared which enables the pacemaker to decrease stimulation rate in the supine position, to increase it in the upright position, and to correlate pacing rate with the increase in physical exercise. There is a good correlation between number of contact changes and the intrinsic heart rate (r = 0.87).
过去,频率适应性起搏器系统发展过程中最重要的特性是确保对体育锻炼有足够的频率响应。但还有其他变量会调节健康心脏的频率;例如心率的体位变化以预防直立性反应,以及夜间固有起搏器频率的下降。因此,我们开发了一种传感器,它不仅能区分休息和活动,还能区分仰卧位和直立位。这种传感器是一种多触点倾斜开关,其中包含一个小汞球。通过测量当球接触众多传感器触点时传感器内的开合次数,就有可能区分不同程度的运动;触针环绕在底板周围。随着运动增加,每次的变化次数几乎呈线性增加。除了根据每次的接触变化次数测量身体活动外,还可以根据外壳内闭合触点的计数和位置确定身体姿势。基于12名志愿者和9名起搏器患者的结果,正在准备一种新算法,使起搏器能够在仰卧位降低刺激频率,在直立位增加刺激频率,并使起搏频率与体育锻炼的增加相关联。接触变化次数与固有心率之间存在良好的相关性(r = 0.87)。