1Division of Physical Therapy, The Ohio State University, USA.
Clin Rehabil. 2013 Nov;27(11):972-82. doi: 10.1177/0269215513487235. Epub 2013 Jun 20.
To investigate the feasibility, acceptability, and safety of a supervised video game exercise program administered via Dance Dance Revolution in individuals with Huntington's disease.
A cross-over, controlled, single-blinded, six-week trial.
Home-based.
Eighteen ambulatory individuals with Huntington's disease (seven male, mean age 50.7 SD 14.7).
Participants played the Dance Dance Revolution game with supervision and the handheld game without supervision for 45 minutes, two days per week for six weeks.
Game play performance and adherence, participant perceptions of the game, safety (vital signs, adverse health changes), spatiotemporal gait measures, Four-Square Step Test, Tinetti Mobility Test, Activities-Specific Balance Confidence Scale, and World Health Organization Quality of Life - Bref, before and after each intervention.
Most participants improved on game play, enjoyed playing the game, and wanted to continue playing after study completion. After playing Dance Dance Revolution, participants showed significant reductions in double support percentage (adjusted mean difference (95% confidence intervals): -2.54% (-4.75, -0.34) for forward walking and -4.18 (-6.89, -0.48) for backward walking) and those with less severe motor symptoms had reductions in heel-to-heel base of support during forward walking. The remaining measures were not significantly impacted by the intervention.
Dance Dance Revolution appears to be a feasible, motivating, and safe exercise intervention for individuals with Huntington's disease.
研究监督式视频游戏运动方案（通过跳舞机实施）用于亨廷顿病患者的可行性、可接受性和安全性。
交叉对照、单盲、六星期试验。
居家。
18 名亨廷顿病患者（7 名男性，平均年龄 50.7 ± 14.7 岁）。
参与者在监督下玩跳舞机游戏和无监督手持游戏，每周两天，每次 45 分钟，共六周。
游戏表现和坚持度、参与者对游戏的看法、安全性（生命体征、不良健康变化）、时空步态测量、四方步测试、Tinetti 活动能力测试、活动特异性平衡信心量表和世界卫生组织生活质量量表-简表，在每次干预前后进行。
大多数参与者的游戏表现有所提高，喜欢玩游戏，并希望在研究结束后继续玩。玩跳舞机后，参与者的双脚支撑百分比显著降低（调整后的平均差异（95%置信区间）：向前走时为-2.54%（-4.75，-0.34），向后走时为-4.18%（-6.89，-0.48）），运动症状较轻的患者在向前走时的脚跟到脚跟支撑基础也有所减少。其余指标未受到干预的显著影响。
跳舞机似乎是一种可行、有激励性且安全的亨廷顿病患者运动干预措施。
