Holý Ondřej, Matoušková Ivanka
Department of Preventive Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic.
Contemp Oncol (Pozn). 2012;16(3):266-72. doi: 10.5114/wo.2012.29298. Epub 2012 Jul 6.
The main purpose of cleanrooms in health care centres is to prevent hospital infections or leakage of a highly infectious agent (the source of haemorrhagic fevers, SARS, etc.) into the ambient environment and subsequently possibly threatening other individuals. Patients with haematological malignancies or after autologous or allogeneic haematopoietic stem cell transplantation (HSCT) rank among immunosuppressed individuals. Prolonged and deep neutropenia is considered a key risk factor of the occurrence of an exogenous infection. One of the possibilities of preventing an exogenous infection in these patients is to place them in a "cleanroom" for the crucial period of time. Cleanrooms are intensive care units with reverse isolation. The final part of the general article below provides an overview of the technology and types of cleanrooms for immunosuppressed patients in compliance with the current recommendations and technical standards.
医疗保健中心洁净室的主要目的是预防医院感染,或防止高传染性病原体(出血热、非典等的病原体)泄漏到周围环境中,进而可能威胁到其他个体。血液系统恶性肿瘤患者或自体或异基因造血干细胞移植(HSCT)后的患者属于免疫抑制个体。长期且严重的中性粒细胞减少被认为是发生外源感染的关键危险因素。在这些患者关键的时间段内将他们安置在“洁净室”是预防外源感染的一种方法。洁净室是具有反向隔离功能的重症监护病房。以下这篇综述文章的最后部分按照当前建议和技术标准,概述了针对免疫抑制患者的洁净室技术和类型。