放射性气道坏死
Radiation-associated airway necrosis.
作者信息
Alraiyes Abdul Hamid, Alraies M Chadi, Abbas Abbas
机构信息
Department of Pulmonary Diseases, Critical Care, and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA.
出版信息
Ochsner J. 2013 Summer;13(2):273-5.
BACKGROUND
Chondronecrosis is one of the complications that occurs after radiation treatment of the chest and mediastinal tumors, with necrosis usually developing months to years after treatment. Upper airway perichondritis and necrosis of the cricoid cartilage, larynx, and upper trachea have been observed as a complication of radiation therapy for head and neck cancers as well. Tracheal chondronecrosis, on the other hand, is a rare complication after radiation treatment.
CASE REPORT
We report a case of delayed chondronecrosis of the distal trachea that developed 8 years after radiation treatment using iodine-125 seeds to treat mediastinal adenocarcinoma.
CONCLUSION
Treatment options for chondronecrosis of the distal trachea are based on the location and extent of the airway chondronecrosis and can be either balloon bronchial dilatation with stent placement or surgical resection and anastomosis.
背景
软骨坏死是胸部和纵隔肿瘤放射治疗后发生的并发症之一，坏死通常在治疗后数月至数年出现。上呼吸道软骨膜炎以及环状软骨、喉和气管上段坏死也被观察到是头颈部癌症放射治疗的并发症。另一方面，气管软骨坏死是放射治疗后罕见的并发症。
病例报告
我们报告一例使用碘-125粒子治疗纵隔腺癌8年后发生的气管远端迟发性软骨坏死病例。
结论
气管远端软骨坏死的治疗方案取决于气道软骨坏死的部位和范围，可采用球囊支气管扩张加支架置入术或手术切除及吻合术。
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