Romanescu D, Gangone E, Boeti M P Sirbu, Zamfir R, Dima S O, Popescu I
Department of General Surgery and Liver Transplantation, Dan Setlacec Fundeni Clinical Institute, Bucharest, Romania.
Chirurgia (Bucur). 2013 May-Jun;108(3):372-80.
The pancreas procurement from brain-dead donors used for pancreatic islet isolation and transplantation, was analyzed between 2007-2012. The pancreas was transported to the Fundeni Clinical Institute and the islet isolation process was performed in the Cell Therapy Laboratory. There were 20 en bloc pancreas-duodenum-spleen procurement during multiorgan harvesting. Eighteen pancreata were used for islet isolation and two were used for whole pancreas transplantation.One pancreas was used for whole pancreas transplant alone and the other one was used for simultaneous pancreas and kidney transplantation. Donor age ranged between 12 and 61 years, with a median age of 35 years old. The donors were 9 females and 11 males. The causes of death were in 8 cases –brain injury, in 7 cases – aneurism rupture, and in 5 cases stroke. The donors’ blood group was A(II) in 11 cases, O(I) in7 cases, and B(III) in 2 cases. The calculated BMI of the donors ranged between 15.6 and 27.8, with a median value of 24.1. The median calculated Vinkers score for our study group was 11. Cold ischemia time ranged between 1.5 and 8 hours,with a median value of 5 hours.
对2007年至2012年间从脑死亡供体获取的用于胰岛分离和移植的胰腺进行了分析。胰腺被运至芬德尼临床研究所，胰岛分离过程在细胞治疗实验室进行。在多器官获取过程中，共进行了20次整块胰腺 - 十二指肠 - 脾脏获取。18个胰腺用于胰岛分离，2个用于全胰腺移植。其中1个仅用于全胰腺移植，另1个用于胰肾联合移植。供体年龄在12岁至61岁之间，中位年龄为35岁。供体中女性9名，男性11名。死亡原因：8例为脑损伤，7例为动脉瘤破裂，5例为中风。供体血型：11例为A(II)型，7例为O(I)型，2例为B(III)型。供体计算得出的BMI在15.6至27.8之间，中位值为24.1。本研究组计算得出的Vinkers评分中位数为11。冷缺血时间在1.5至8小时之间，中位值为5小时。
