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N-(2-Bromo-4-methyl-phen-yl)-2-(5-methyl-2-phenyl-pyrazolo-[1,5-a]pyrimidin-7-yl)acetamide.

作者信息

Bassoude Ibtissam, Berteina-Raboin Sabine, Essassi El Mokhtar, Guillaumet Gérald, El Ammari Lahcen

机构信息

Laboratoire de Chimie Organique Hétérocyclique URAC21, Pôle de Compétences Pharmacochimie, Université Mohammed V-Agdal, Avenue Ibn Battouta, BP 1014, Rabat, Morocco ; Institut de Chimie Organique et Analytique, Université d'Orléans, UMR CNRS 6005, BP 6759, 45067 Orléans Cedex 2, France.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2013 May 4;69(Pt 6):o829. doi: 10.1107/S1600536813011811. Print 2013 Jun 1.

DOI:10.1107/S1600536813011811
PMID:23795019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3684917/
Abstract

The fused pyrazole and pyrimidine rings in the title compound, C22H19BrN4O, are almost coplanar, their planes being inclined to one another by 2.08 (13)°. The dihedral angles formed by the mean plane of the fused ring system and the phenyl and benzene rings are 16.21 (4) and 82.84 (4)°, respectively. An intra-molecular N-H⋯N hydrogen bond is observed. In the crystal, mol-ecules form inversion dimers via pairs of C-H⋯O hydrogen bonds. π-π inter-actions, with centroid-centroid distances of 3.4916 (9) Å, connect the dimers into a three-dimensional network.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/3684917/9b52d4cb9e5a/e-69-0o829-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/3684917/db48a96ce96a/e-69-0o829-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/3684917/9b52d4cb9e5a/e-69-0o829-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/3684917/db48a96ce96a/e-69-0o829-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/607a/3684917/9b52d4cb9e5a/e-69-0o829-fig2.jpg

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