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阴道镜检查作为宫颈上皮内瘤变(CIN)和微浸润癌管理策略的一种方法。

Colposcopy as a method of management strategy in CIN and microinvasive cancer.

作者信息

Madej J, Madej J G

机构信息

Institute of Obstetrics and Gynecology, Medical Academy of Cracow, Poland.

出版信息

Eur J Gynaecol Oncol. 1990;11(2):117-22.

PMID:2379510
Abstract

During nearly 40 years of using colposcopy, an original management strategy in CIN and early cervical cancer was developed and confirmed in 2 study groups of cervical lesions containing respectively 1228 and 6001 cases. This approach is based on colposcopy as the main method in early detection of CIN and cancer, with supplementary cytology in necessary cases, and on a coloposcopic-histological staging of these lesions for treatment qualification. Colposcopy alone is a fairly adequate method for diagnosis of 60% of examined cases, and coloscopy with directed biopsy in the next 20% of colposcopically highly suspect findings. Only in the remaining 20% of colposcopically less suspect findings and in the cases of "unsatisfactory colposcopy", supplementary was cytology required. In this study colposcopy findings connected with histological evaluation of the specimens provided a basic way for determining the advancement of processes and the selection method for the appropriate type and extent of treatment. CIN 1 and 2 and small focuses of CIN 3 including CIS entirely visible on the ectocervix, in childless young women were treated by cryosurgery. In all remaining cases of CIN 3, the basic therapeutic method was cold-knife conization. In exceptional cases simple hysterectomy can be a more adequate treatment. Depending on our colposcopic-histological staging, in Stage IA1--conization, whereas in Stage IA2--a moderately extended hysterectomy should be optionally performed. The management strategy introduced is an economical, fully effective and quick way of detection and selection of the method for the treatment of CIN and early cervical cancer.

摘要

在近40年的阴道镜使用过程中,针对CIN(宫颈上皮内瘤变)和早期宫颈癌制定了一种原始的管理策略,并在两个分别包含1228例和6001例宫颈病变的研究组中得到证实。该方法以阴道镜作为早期检测CIN和癌症的主要方法,必要时辅以细胞学检查,并根据这些病变的阴道镜-组织学分期来确定治疗方案。仅阴道镜检查就足以诊断60%的受检病例,对于另外20%阴道镜高度可疑的发现则进行阴道镜引导下活检。仅在其余20%阴道镜可疑程度较低的发现以及“不满意阴道镜检查”的病例中才需要补充细胞学检查。在本研究中,与标本组织学评估相关的阴道镜检查结果为确定病情进展以及选择合适的治疗类型和范围提供了基本方法。对于宫颈外口完全可见的CIN 1和2以及CIN 3小病灶(包括原位癌),未生育的年轻女性采用冷冻手术治疗。在所有其余的CIN 3病例中,基本治疗方法是冷刀锥切术。在特殊情况下,单纯子宫切除术可能是更合适的治疗方法。根据我们的阴道镜-组织学分期,IA1期行锥切术,而IA2期可选择行适度扩大的子宫切除术。所引入的管理策略是一种经济、高效且快速的检测和选择CIN和早期宫颈癌治疗方法的途径。

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