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红细胞分布宽度与 2 型糖尿病患者运动后的高血压反应。

Red cell distribution width and hypertensive response to exercise in patients with type 2 diabetes mellitus.

机构信息

Department of Cardiology, Medical School, Cumhuriyet University , Sivas , Turkey .

出版信息

Clin Exp Hypertens. 2014;36(1):32-5. doi: 10.3109/10641963.2013.783050. Epub 2013 Jun 24.

Abstract

OBJECTIVE

There is no study about hypertensive response to exercise (HRE), which is a marker of unborn hypertension (HT), and red cell distribution width (RDW) association, in diabetic normotensive patients. So, we aimed to investigate any correlation among RDW and HRE in normotensive type 2 diabetic patients.

METHODS

Consecutive type 2 diabetic patients without history of HT and with normal blood pressure (BP) on ambulatory BP monitoring were included to the study. We divided the patients into two groups depending on their peak systolic BP on exercise; HRE (Group 1) or normal response to exercise (Group 2).

RESULTS

Data of 75 diabetic patients (51.9 ± 9.7) were analyzed (31 male (48%)). Their mean RDW was 13.11 ± 0.46. Patients with HRE were significantly older than patients without HRE. Smoking was more frequent in Group 2. Gender distribution and body mass index were similar between the groups. Else hemoglobin, hematocrit, red blood cell count and RDW values were not significantly different. Office systolic BP and diastolic BP, daytime and 24-h systolic BP were significantly higher in Group 1 but heart rate was similar between the groups.

CONCLUSIONS

This study revealed that RDW do not differ between diabetic normotensive patients with HRE or not.

摘要

目的

目前尚无研究探讨运动性高血压反应(HRE)与红细胞分布宽度(RDW)之间的关系,而 HRE 是胎儿高血压(HT)的一个标志物。因此,我们旨在研究正常血压 2 型糖尿病患者中 RDW 与 HRE 之间是否存在相关性。

方法

连续纳入无 HT 病史且动态血压监测血压正常的 2 型糖尿病患者进行研究。根据运动时收缩压峰值,我们将患者分为 HRE 组(Group 1)或运动时正常反应组(Group 2)。

结果

共分析了 75 例糖尿病患者(51.9 ± 9.7)的数据(男性 31 例(48%))。他们的平均 RDW 为 13.11 ± 0.46。HRE 组患者明显比无 HRE 组患者年龄更大。HRE 组患者吸烟更为频繁。两组间的性别分布和体重指数相似。但血红蛋白、红细胞压积、红细胞计数和 RDW 值无显著差异。HRE 组患者诊室收缩压和舒张压、日间和 24 小时收缩压明显更高,但心率相似。

结论

本研究表明,HRE 正常的糖尿病正常血压患者与 HRE 异常的患者之间 RDW 无差异。

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