Ondounda M, Gaudong Mbethe L, Mounguengui D, Magne C, Nzenze J R
Service de médecine interne, hôpital d'instruction des armées Omar-Bongo-Ondimba, PK9, BP 20404, Libreville, Gabon.
Med Sante Trop. 2013 Jul-Sep;23(3):304-7. doi: 10.1684/mst.2013.0180.
To determine the main causes of lymphadenopathies and their clinical characteristics in Gabon.
This retrospective study analyzed the records of patients hospitalized in the medical department at the Military Hospital of Libreville (Gabon) from January 2010 through December 2011 who presented one or more lymphadenopathies.
The study included 78 patients (45 men, 33 women), with a mean age of 42.2 ± 15.9 years. Lymphadenopathies were superficial in 67.9% of cases, abdominal in 42% of cases and mediastinal in 24% of cases. Both deep and superficial locations were noted in 26% (20 cases). Weight loss (63%), fever (56%), asthenia (54%), hepatomegaly (26%), and splenomegaly (20%) were the clinical signs most frequently associated with lymphadenopathy. The main diagnoses were tuberculosis (52%, 41 cases) and non-Hodgkin's lymphoma (11%, 9 cases). Infection with human immunodeficiency virus (HIV) was found in 47% of cases.
Tuberculosis remains the most frequent cause of lymphadenopathy in our setting. HIV testing should be routinely performed in all patients with lymphadenopathy.
确定加蓬淋巴结病的主要病因及其临床特征。
这项回顾性研究分析了2010年1月至2011年12月在加蓬利伯维尔军事医院内科住院的出现一处或多处淋巴结病的患者记录。
该研究纳入了78例患者（45例男性，33例女性），平均年龄为42.2±15.9岁。67.9%的病例中淋巴结病为浅表性，42%的病例为腹部淋巴结病，24%的病例为纵隔淋巴结病。26%（20例）患者同时存在深部和浅表淋巴结病。体重减轻（63%）、发热（56%）、乏力（54%）、肝肿大（26%）和脾肿大（20%）是与淋巴结病最常相关的临床体征。主要诊断为结核病（52%，41例）和非霍奇金淋巴瘤（11%，9例）。47%的病例发现感染了人类免疫缺陷病毒（HIV）。
在我们的研究环境中，结核病仍然是淋巴结病最常见的病因。对所有淋巴结病患者应常规进行HIV检测。
