Department of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, India. Correspondence to: Dr Anu Mary Alexander, Department of Community Medicine, Christian Medical College, Vellore, 632 002, Tamil Nadu, India.
Indian Pediatr. 2013 Nov 8;50(11):1020-4. doi: 10.1007/s13312-013-0282-y. Epub 2013 Jun 5.
The objectives of the study were to estimate gestational age specific birthweight centiles from healthy pregnancies in a defined rural block and compare the under-two month mortality rates in those belonging to the lowest and highest centile groups.
Retrospective chart review.
Routine data collected regarding all pregnancies, births and deaths occurring in Kaniyambadi, a rural block in Southern India, between 2003 to 2012.
All singleton live newborns of women without known major antenatal risk factors.
Gestational age- and sex-specific birthweight centile curves were created using the LMS method. Mortality rates for the first two months of life were calculated for those in various centile groups.
The median birthweight at term was lower for the study subjects as compared to the median birth weights in the WHO child growth standards 2006, the US and the UK standards. Mortality rates for those with birthweights both below the 3rd centile as well as above the 97th centile higher than for those between 3rd and 97th centiles.
While absolute values of birthweights were lower than the WHO 2006 child growth standards there was a J shaped curve of birthweight and mortality. This suggests that in a given population, mortality increases at extremes of birthweights, even if some of these birthweights may be considered normal by other standards.
本研究旨在为一个特定的农村地区的健康妊娠估计特定胎龄的出生体重百分位数,并比较属于最低和最高百分位组的婴儿在两个月内的死亡率。
回顾性图表审查。
在印度南部的卡尼扬巴迪农村地区,收集了 2003 年至 2012 年期间所有妊娠、分娩和死亡的常规数据。
所有单胎活产新生儿,其母亲无明显产前重大危险因素。
采用 LMS 方法绘制胎龄和性别特异性出生体重百分位数曲线。计算了不同百分位组婴儿在生命头两个月的死亡率。
与 2006 年世卫组织儿童生长标准、美国和英国标准相比,研究对象的足月出生体重中位数较低。出生体重低于第 3 百分位和高于第 97 百分位的婴儿死亡率均高于第 3 至第 97 百分位的婴儿。
虽然出生体重的绝对值低于世卫组织 2006 年儿童生长标准,但出生体重和死亡率呈 J 形曲线。这表明,在特定人群中,即使某些出生体重按其他标准可能被认为是正常的,但在出生体重的极端情况下死亡率会增加。