Department of Internal Medicine at Mount Sinai Medical Center, Florida, USA.
J Gastrointestin Liver Dis. 2013 Jun;22(2):199-204.
The hydroxy-methyl-glutaryl-CoA reductase inhibitors (statins) are used extensively in the treatment of dyslipidemia, and for the prevention and treatment of coronary artery disease and stroke. They have also demonstrated a benefit in a variety of other disease processes through their non-lipid lowering properties, known as pleiotropic effects. Our paper serves as a focused and updated discussion of the pleiotropic effects of statins in gastrointestinal disorders.
羟甲基戊二酰辅酶 A 还原酶抑制剂（他汀类药物）广泛用于治疗血脂异常，以及预防和治疗冠状动脉疾病和中风。通过其非降脂特性（称为多效作用），它们在各种其他疾病过程中也表现出益处。我们的论文是对他汀类药物在胃肠道疾病中的多效作用的重点和更新讨论。
