Kayabali I, Gökçora I H, Kayabali M
Department of General Surgery, Ankara University Hospital, Cebeci, Turkey.
Int Surg. 1990 Apr-Jun;75(2):96-100.
Of the 257 typhoid enteric perforations analysed at the Departments of General and Paediatric Surgery, Ankara University Hospital, through the years 1979-1986, 74.9% were males, while the patients mean age was 35.8 years. The early signs and symptoms averaged 5.9 days. The corresponding percentages for the occurrence of abdominal pain, fever, nausea and vomiting and central nervous system disorders which constituted the clinical findings were 97.27, 51, 61.2 and 18 respectively. While the mean value for the white blood count ranged around 6600, only 61.9% of the cases had diagnostic findings in their erect abdominal roentgenograms. The standard method for the treatment of typhoid enteric perforations is still presently primary suturing of the perforated viscus and peritoneal drainage. Despite the use and misuse of a large variety of antibiotics, typhoid perforations still have a high morbidity of 74.1% and a mortality of 31.4%. Generalized peritonitis (78.4%), is considered to be to the most important cause in both situations.
在安卡拉大学医院普通外科和小儿外科对1979年至1986年间分析的257例伤寒肠穿孔病例中，74.9%为男性，患者平均年龄为35.8岁。早期症状平均持续5.9天。构成临床表现的腹痛、发热、恶心呕吐及中枢神经系统紊乱的发生率分别为97.27%、51%、61.2%和18%。白细胞计数平均值约为6600，仅61.9%的病例在立位腹部X线片中出现诊断性表现。目前治疗伤寒肠穿孔的标准方法仍是对穿孔脏器进行一期缝合及腹腔引流。尽管使用了各种各样的抗生素，且存在滥用情况，但伤寒穿孔的发病率仍高达74.1%，死亡率为31.4%。弥漫性腹膜炎（78.4%）被认为是导致这两种情况的最重要原因。
