U.C.O. Di Radiologia, Dipartimento di Scienze Mediche, Tecnologiche e Traslazionali, Azienda Ospedaliero-Universitaria di Trieste, Strada di Fiume 447, 34100, Trieste, Italy,
Radiol Med. 2013 Oct;118(7):1184-98. doi: 10.1007/s11547-013-0955-6. Epub 2013 Jun 25.
This study was done to evaluate by direct comparison the image quality of magnetic resonance urography (MRU) and computed tomography urography (CTU) and to assess the diagnostic confidence of the two techniques in detecting urothelial malignancy in patients with haematuria
Thirty-five patients with haematuria underwent both CTU and MRU. Two different investigators evaluated calyceal, renal pelvis, ureteral and bladder visibility. Their diagnostic confidence in detecting urothelial malignancy with the two procedures was assessed. A Wilcoxon matched-pairs test was performed to compare results. Inter-reader agreement was calculated by weighted kappa (WK) statistic. Patient history (further examinations, cystoscopy and histological specimens) was considered as reference standard to calculate receiver operating characteristic (ROC) curves of diagnostic confidence.
CTU provided better visibility of urothelial structures (p<0.01) and allowed for greater diagnostic confidence (ROC area 0.994 vs. 0.938) than MRU, with a good inter-reader agreement (WK=0.62). Nevertheless, in obstructive patients with impaired excretory function, MRU, thanks to the static-fluid technique, offered better visualisation than CTU.
There is a potential role for MRU in urinary tract imaging, but as diagnostic confidence in detecting urothelial malignancy is poorer than in CTU, it might be stareserved for patients at low risk for malignancy and for evaluating obstructed patients.
本研究旨在通过直接比较磁共振尿路成像(MRU)和计算机断层尿路成像(CTU)的图像质量,评估这两种技术在检测血尿患者尿路恶性肿瘤中的诊断信心。
35 例血尿患者同时行 CTU 和 MRU 检查。两名不同的研究者评估了肾盂、输尿管和膀胱的显影情况。评估了他们使用两种方法检测尿路恶性肿瘤的诊断信心。采用 Wilcoxon 配对检验对结果进行比较。采用加权 kappa(WK)统计评估读者间的一致性。患者的病史(进一步检查、膀胱镜检查和组织学标本)被认为是计算诊断信心的接收者操作特征(ROC)曲线的参考标准。
CTU 提供了更好的尿路结构显影(p<0.01),并能提供更高的诊断信心(ROC 曲线下面积 0.994 比 0.938),读者间的一致性良好(WK=0.62)。然而,在存在排泄功能障碍的梗阻患者中,MRU 由于采用了静态液体技术,提供了比 CTU 更好的可视化效果。
MRU 在尿路成像中具有潜在的作用,但由于检测尿路恶性肿瘤的诊断信心不如 CTU,因此可能更适用于恶性肿瘤风险低的患者和评估梗阻患者。