Jacobs A, Delrée M, Desprechins B, Otten J, Jonckheer M H, Mertens J, Ham H R, Piepsz A
Departement Nucleaire Geneeskunde, AZ VUB, Brussel, België.
J Belge Radiol. 1990 Jun;73(3):173-9.
Since the early eighties, *I-MIBG (= *I-metaiodobenzylguanidine), which is stored in the neurotransmitter storage granules of chromaffin cells, has been increasingly used for the detection of pheochromocytomas and allied sympathoadrenal pathologies. The aim of this paper is to illustrate, by means of clinical examples, the role of *I-MIBG-scintigraphy in child neuroblastoma and to underline its original place, compared with other imaging techniques, in determining the neuro-ectodermal origin of a tumor as well as in establishing the extension of the lesions at the time of diagnosis and during follow-up.
自20世纪80年代初以来，131I-间碘苄胍（131I-MIBG）储存于嗜铬细胞的神经递质储存颗粒中，越来越多地用于检测嗜铬细胞瘤及相关的交感肾上腺系统疾病。本文旨在通过临床实例说明131I-MIBG闪烁扫描术在儿童神经母细胞瘤中的作用，并强调与其他成像技术相比，其在确定肿瘤的神经外胚层起源以及在诊断时和随访期间确定病变范围方面的独特地位。
