Papasotiriou Marios, Papachristou Evangelos, Marangos Markos, Koukoulaki Maria, Savvidaki Eirini, Kalliakmani Pantelitsa, Goumenos Dimitrios S
Department of Internal Medicine, University Hospital of Patras, Patras, Greece.
Clin Nephrol. 2013 Jul;80(1):75-8. doi: 10.5414/cn107479.
Although cytomegalovirus (CMV) disease in CMV IgM/IgG-negative renal transplant recipients from CMV-positive donors (D+/R-) can occur after discontinuation of prophylaxis treatment as a flu-like syndrome or tissue invasive disease, involvement of the central nervous system is rare. Here, we report a case of CMV polyradiculopathy 6 months after renal transplantation that presented as a Guillain-Barre like syndrome and was successfully treated with foscarnet. This case highlights an uncommon aspect of CMV invasive disease which we should keep in mind in CMV (D+/R-) renal transplant recipients.
尽管来自巨细胞病毒(CMV)阳性供体的CMV IgM/IgG阴性肾移植受者(D+/R-)在预防治疗中断后可能会发生CMV疾病,表现为流感样综合征或组织侵袭性疾病,但中枢神经系统受累情况罕见。在此,我们报告1例肾移植6个月后发生CMV多发性神经根病的病例,该病例表现为吉兰-巴雷综合征样症状,并通过膦甲酸钠成功治愈。该病例突出了CMV侵袭性疾病的一个不常见方面,我们在CMV(D+/R-)肾移植受者中应予以关注。