骨骼肌干细胞

Skeletal muscle stem cells.

作者信息

Kao Grace W, Lamb Elizabeth K, Kao Race L

机构信息

Department of Surgery, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN, USA.

出版信息

Methods Mol Biol. 2013;1036:19-32. doi: 10.1007/978-1-62703-511-8_2.

DOI:10.1007/978-1-62703-511-8_2

PMID:23807783

Abstract

Skeletal muscle satellite cells (myoblasts) are the primary stem cells of skeletal muscle which contribute to growth, maintenance, and repair of the muscles. Satellite cells are the first stem cells used for cellular cardiomyoplasty more than 20 years ago. The isolation, culture, labeling, and identification of satellite cells are described in detail here. The implantation and outcomes of cellular cardiomyoplasty using satellite cells have been summarized in the previous chapter (Chapter 1).

摘要

骨骼肌卫星细胞（成肌细胞）是骨骼肌的主要干细胞，对肌肉的生长、维持和修复起作用。卫星细胞是20多年前最早用于细胞心肌成形术的干细胞。本文详细描述了卫星细胞的分离、培养、标记和鉴定。上一章（第1章）总结了使用卫星细胞进行细胞心肌成形术的植入方法和结果。