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剖宫产术后慢性疼痛:一项澳大利亚队列研究。

Chronic pain after caesarean delivery: an Australian cohort.

作者信息

Liu T T, Raju A, Boesel T, Cyna A M, Tan S G M

机构信息

Department of Anaesthesia and Pain Management, Nepean Hospital, Penrith, New South Wales.

出版信息

Anaesth Intensive Care. 2013 Jul;41(4):496-500. doi: 10.1177/0310057X1304100410.

Abstract

We investigated the incidence of and risk factors for persistent pain after caesarean delivery. Over a 12-month period, women having caesarean delivery were recruited prospectively at an Australian tertiary referral centre. Demographic, anaesthetic and surgical data were collected and at 24 hour follow-up, women were assessed for immediate postoperative pain and preoperative expectations of pain. Long-term telephone follow-up was conducted at two and 12 months postoperatively. Complete data were obtained from 426 of 469 women initially recruited (90.6%). The incidence of persistent pain at the abdominal wound at two months was 14.6% (n=62) but subsequently reduced to 4.2% (n=18) at 12 months. At two months, 33 patients (7.8%) experienced constant or daily pain. At 12 months, five patients (1.1%) continued to have constant or daily pain which was mild. There was no apparent increase in incidence of persistent pain associated with general versus regional anaesthesia (relative risk [RR] 0.89, 95% confidence interval [CI] 0.49 to 1.6); emergency vs elective procedure (RR 0.65, 95% CI 0.39 to 1.07); higher acute pain scores (RR 1.1, 95% CI 0.69 to 1.75); or history of previous caesarean delivery (RR 0.81, 95% CI 0.50 to 1.33). Persistent pain, usually of a mild nature, is reported by some women two months after their caesarean delivery, but by 12 months less than 1% of women had pain requiring analgesia or affecting mood or sleep. All declined a pain clinic review. Clinicians and patients can be reassured that caesarean delivery is unlikely to lead to severe persistent pain in the long-term.

摘要

我们调查了剖宫产术后持续性疼痛的发生率及危险因素。在12个月的时间里,澳大利亚一家三级转诊中心前瞻性地招募了行剖宫产术的女性。收集了人口统计学、麻醉和手术数据,并在术后24小时进行随访,评估女性术后即刻疼痛情况以及术前对疼痛的预期。术后2个月和12个月进行长期电话随访。最初招募的469名女性中有426名(90.6%)获得了完整数据。术后2个月时腹部伤口持续性疼痛的发生率为14.6%(n = 62),但在12个月时降至4.2%(n = 18)。术后2个月时,33例患者(7.8%)经历了持续性或每日疼痛。术后12个月时,5例患者(1.1%)仍有轻度的持续性或每日疼痛。与全身麻醉相比,区域麻醉并未明显增加持续性疼痛的发生率(相对危险度[RR] 0.89,95%置信区间[CI] 0.49至1.6);急诊手术与择期手术相比(RR 0.65,95% CI 0.39至1.07);急性疼痛评分较高(RR 1.1,95% CI 0.69至1.75);或既往有剖宫产史(RR 0.81,95% CI 0.50至1.33)。一些女性在剖宫产术后2个月报告有持续性疼痛,通常程度较轻,但到12个月时,不到1%的女性有需要镇痛或影响情绪或睡眠的疼痛。所有人都拒绝了疼痛门诊复查。临床医生和患者可以放心,剖宫产术长期来看不太可能导致严重的持续性疼痛。

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