Prendki Virginie, Marmor Simon, Zeller Valérie, Lhotellier Luc, Mégraud Francis, Desplaces Nicole
Service d'Orthopédie, Groupe Hospitalier Diaconesses Croix Saint Simon, Paris, France.
Scand J Infect Dis. 2013 Sep;45(9):706-10. doi: 10.3109/00365548.2013.800225. Epub 2013 Jul 1.
Few cases of Campylobacter prosthetic joint infection (PJI) have been reported so far. We describe the demographic characteristics, underlying conditions, clinical features, treatment, and outcome of 8 patients with Campylobacter PJI in our hospital. All strains were confirmed at the French National Reference Center for Campylobacter and Helicobacter. Seven patients were infected with C. fetus and 1 with C. jejuni. Most patients were elderly and immunocompromised. Four had bacteremia, one of these with a pacemaker endocarditis. All the patients received at least 3 months of antibiotic treatment and 6 were treated surgically. The outcome was favorable at 2 years of follow-up in all except for 1 patient. Campylobacter PJI cases are rare but likely to become more frequent. C. fetus bacteremia should motivate physicians to look for a secondary localization such as a Campylobacter PJI.
迄今为止，弯曲杆菌人工关节感染（PJI）的病例报道较少。我们描述了我院8例弯曲杆菌PJI患者的人口统计学特征、基础疾病、临床特征、治疗方法及预后。所有菌株均在法国国家弯曲杆菌和幽门螺杆菌参考中心得到确认。7例患者感染胎儿弯曲杆菌，1例感染空肠弯曲杆菌。大多数患者为老年人且免疫功能低下。4例发生菌血症，其中1例合并起搏器心内膜炎。所有患者均接受了至少3个月的抗生素治疗，6例接受了手术治疗。除1例患者外，所有患者在2年随访时预后良好。弯曲杆菌PJI病例罕见，但可能会变得更加常见。胎儿弯曲杆菌菌血症应促使医生寻找继发性感染部位，如弯曲杆菌PJI。
