Department of Neurosurgery, The Royal London Hospital, Whitechapel, London E1 1BB, UK.
J Clin Neurosci. 2013 Aug;20(8):1045-56. doi: 10.1016/j.jocn.2013.03.008. Epub 2013 Jun 25.
Optic nerve sheath meningiomas account for a third of all intrinsic tumours of the optic nerve. Despite their classification as histologically benign tumours they cause progressive visual loss that often leads to blindness if left untreated. Recent therapeutic advances have increased the treatment options available to clinicians but patient management remains controversial. We systematically review the progress made in the diagnosis and management of optic nerve sheath meningiomas, clarify current best practice, and suggest future avenues for research.
视神经鞘脑膜瘤占视神经内所有肿瘤的三分之一。尽管它们被归类为组织学良性肿瘤,但如果不治疗,它们会导致进行性视力丧失,最终导致失明。最近的治疗进展增加了临床医生可用的治疗选择,但患者管理仍然存在争议。我们系统地回顾了视神经鞘脑膜瘤的诊断和治疗进展,阐明了当前的最佳实践,并提出了未来的研究方向。