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关节镜下前交叉韧带重建术后深静脉血栓形成:100 例患者的前瞻性队列研究。

Deep vein thrombosis after arthroscopic anterior cruciate ligament reconstruction: a prospective cohort study of 100 patients.

机构信息

Department of Orthopaedic Surgery, Isala Klinieken, Zwolle, The Netherlands.

出版信息

Arthroscopy. 2013 Jul;29(7):1211-6. doi: 10.1016/j.arthro.2013.04.015.

DOI:10.1016/j.arthro.2013.04.015
PMID:23809456
Abstract

PURPOSE

To establish the incidence of venous thromboembolic complications as detected by bilateral complete compression ultrasonography (CCUS) after arthroscopic anterior cruciate ligament (ACL) reconstruction without thromboprophylaxis.

METHODS

We performed a prospective cohort study to establish the incidence of venous thromboembolic complications after arthroscopic ACL reconstruction, as detected by bilateral CCUS at 14 days (range, 11 to 17 days) postoperatively. One hundred consecutive patients underwent bilateral extended ultrasonography.

RESULTS

One hundred predominantly European patients with a mean age of 30 ± 10 years and mean body mass index of 25 ± 4 underwent ACL reconstruction with a mean operative duration of 68 ± 23 minutes and a tourniquet time of 76 ± 23 minutes. In 84% of patients an autologous hamstring graft was used, in 14% a bone-patellar tendon-bone graft was used, and 2 patients received an allograft. Of 100 patients, 9 (incidence, 9%; 95% confidence interval, 4.2 to 16.4) showed asymptomatic proximal or distal deep vein thrombosis on CCUS, of whom 4 (incidence, 4%; 95% confidence interval, 1.1 to 9.9) were symptomatic. A nonfatal pulmonary embolus developed in 1 patient during the 8-week follow-up period.

CONCLUSIONS

This study shows that the incidence of venous thromboembolism after arthroscopic ACL reconstruction is relatively high; a 9% incidence of asymptomatic proximal or distal deep vein thrombosis was found, whereas 4% of patients were symptomatic. Further research is recommended to assess the need for thromboprophylaxis in patients undergoing ACL reconstruction, especially when risk factors are present.

LEVEL OF EVIDENCE

Level IV, case series.

摘要

目的

通过双侧完全压迫超声(CCUS)检测,确定关节镜下前交叉韧带(ACL)重建术后不进行血栓预防的情况下静脉血栓栓塞并发症的发生率。

方法

我们进行了一项前瞻性队列研究,以确定关节镜 ACL 重建后通过双侧 CCUS 在术后 14 天(范围为 11 至 17 天)检测到的静脉血栓栓塞并发症的发生率。100 例连续患者接受了双侧扩展超声检查。

结果

100 例主要为欧洲患者,平均年龄为 30 ± 10 岁,平均体重指数为 25 ± 4,接受 ACL 重建,平均手术时间为 68 ± 23 分钟,止血带时间为 76 ± 23 分钟。84%的患者使用自体腘绳肌移植物,14%的患者使用骨-髌腱-骨移植物,2 例患者接受同种异体移植物。100 例患者中,9 例(发生率为 9%;95%置信区间为 4.2%至 16.4%)在 CCUS 上显示无症状的近端或远端深静脉血栓形成,其中 4 例(发生率为 4%;95%置信区间为 1.1%至 9.9%)有症状。1 例患者在 8 周随访期间发生非致命性肺栓塞。

结论

本研究表明,关节镜 ACL 重建后静脉血栓形成的发生率相对较高;发现无症状的近端或远端深静脉血栓形成的发生率为 9%,而 4%的患者有症状。建议进一步研究评估在接受 ACL 重建的患者中进行血栓预防的必要性,尤其是存在危险因素时。

证据水平

IV 级,病例系列。

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