Baldauf J-J, Baulon E, Thoma V, Woronoff A-S, Akladios C Y
Département de gynécologie obstétrique, hôpital de Hautepierre, hôpitaux universitaires de Strasbourg, 67098 Strasbourg cedex, France.
J Gynecol Obstet Biol Reprod (Paris). 2013 Oct;42(6):534-40. doi: 10.1016/j.jgyn.2013.05.004. Epub 2013 Jul 1.
The obstetrical consequences of conisation for cervical intraepithelial neoplasia (CIN) should be considered since patients affected by these lesions are actually younger and most often desire further pregnancies. The loop electrosurgical excision procedure (LEEP), which is currently mostly used, achieves cure rate varying according to the authors between 80 and 95%. However, the most recent data show an increase of obstetrical morbidity, especially prematurity, after LEEP excision. As the frequency and severity of prematurity is correlated to the size and depth of the LEEP, we should minimize as much as possible the resection for these young patients.
由于患有这些病变的患者实际上较为年轻，且大多希望进一步怀孕，因此应考虑宫颈锥切术治疗宫颈上皮内瘤变（CIN）的产科后果。目前最常用的环形电切术（LEEP），其治愈率根据不同作者报道在80%至95%之间。然而，最新数据显示，LEEP切除术后产科发病率有所增加，尤其是早产。由于早产的频率和严重程度与LEEP的大小和深度相关，我们应尽可能减少对这些年轻患者的切除范围。
