von Domarus C, Beil F T, Seitz S, Rüther W, Zustin J
Klinik und Poliklinik für Orthopädie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.
Orthopade. 2013 Aug;42(8):658-62. doi: 10.1007/s00132-013-2137-6.
The pathophysiological mechanisms of palmar fibromatosis (Dupuytren's contracture) are still not yet fully understood. In the vast majority of cases, however, reactive changes and reparative processes of tendon tissue can easily be ruled out by clinical and histopathological investigations. This article presents the case of a 62-year-old male patient suffering from palmar fibromatosis associated with a failed silicon spacer of the lunate bone 30 years after index surgery. Although silicon wear particles were observed in distal locations, proximal tendon tissues showed changes consistent with a degenerative palmar fibromatosis in the absence of a pathological wear reaction. The findings are discussed in the light of the current literature on Dupuytren's contracture.
掌腱膜纤维瘤病(杜普伊特伦挛缩症)的病理生理机制尚未完全明确。然而,在绝大多数病例中,通过临床和组织病理学检查很容易排除肌腱组织的反应性改变和修复过程。本文介绍了一例62岁男性患者,该患者在首次手术30年后发生掌腱膜纤维瘤病,并伴有月骨硅间隔物失效。尽管在远端部位观察到硅磨损颗粒,但在近端肌腱组织中,在没有病理性磨损反应的情况下,出现了与退行性掌腱膜纤维瘤病一致的变化。本文根据目前关于杜普伊特伦挛缩症的文献对这些发现进行了讨论。