马的颈静脉血栓性静脉炎：纤维蛋白溶解、血栓形成及临床管理综述
Jugular thrombophlebitis in horses: a review of fibrinolysis, thrombus formation, and clinical management.
作者信息
Dias Deborah Penteado Martins, de Lacerda Neto José Corrêa
机构信息
Departamento de Clínica e Cirurgia Veterinária, Faculdade de Ciências Agrárias e Veterinárias - FCAV/Unesp, Brazil.
出版信息
Can Vet J. 2013 Jan;54(1):65-71.
Abstract
Thrombophlebitis of the jugular vein is commonly observed in horses, particularly during intensive care, and leads to local and systemic inflammatory responses as well as head and neck circulatory impairment. Thrombolytic therapy is widely used in human practice with the aim of thrombus dissolution and recanalization of the injured vessels. There are similarities between human and horse coagulation and fibrinolytic processes. This review examines the fibrinolytic system, thrombus formation, and the clinical management of jugular thrombophlebitis, including thrombolytic therapy. There is evidence that early regional thrombolytic therapy for jugular thrombophlebitis in horses may be effective to achieve sustained recanalization.
摘要
颈静脉血栓性静脉炎在马匹中很常见，尤其是在重症监护期间，会导致局部和全身炎症反应以及头颈部循环障碍。溶栓治疗在人类医疗实践中被广泛用于溶解血栓和使受损血管再通。人与马的凝血和纤溶过程存在相似之处。本文综述了纤溶系统、血栓形成以及颈静脉血栓性静脉炎的临床管理，包括溶栓治疗。有证据表明，对马匹颈静脉血栓性静脉炎进行早期局部溶栓治疗可能有效地实现持续再通。
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