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外阴结节病:病例报告及文献复习。

Vulvar sarcoidosis: case report and review of the literature.

机构信息

De[artment of Dermatology, CHUM hôpital St-Luc, University of Montreal, Montreal, Canada.

出版信息

J Cutan Med Surg. 2013 Jul-Aug;17(4):287-90. doi: 10.2310/7750.2012.12083.

Abstract

BACKGROUND

Sarcoidosis is a multisystemic disorder of unknown etiology that can affect multiple organs, including the lungs, skin, and eyes. Vulvar sarcoidosis has anecdotally been reported.

OBJECTIVE

The aim of this article is to describe a case of vulvar sarcoidosis and review the few cases that have been reported.

METHODS

We report the case of a 39-year-old woman who presented to the dermatologist with a 2-year history of vulvar pruritus.

RESULTS

Examination revealed infiltrated plaques on the vulva and perianal region. The biopsy demonstrated well-defined, non-necrotizing granulomas in the dermis. Further investigation revealed hilar adenopathy consistent with sarcoidosis. The patient responded well to topical corticosteroids.

CONCLUSION

In the presence of granulomatous lesions of the genital region, infectious causes, foreign body reaction, Crohn disease, and sarcoidosis should be part of the differential diagnosis.

摘要

背景

结节病是一种病因不明的多系统疾病,可影响多个器官,包括肺、皮肤和眼睛。外阴结节病已有报道。

目的

本文旨在描述一例外阴结节病,并复习已报道的少数病例。

方法

我们报告了一例 39 岁女性患者,因外阴瘙痒 2 年来皮肤科就诊。

结果

检查发现外阴和肛周区域有浸润性斑块。活检显示真皮内界限清楚的非坏死性肉芽肿。进一步检查发现肺门淋巴结肿大符合结节病。患者对外用皮质类固醇反应良好。

结论

在存在生殖器区域的肉芽肿性病变时,应考虑感染性病因、异物反应、克罗恩病和结节病等鉴别诊断。

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