Department of Pediatrics, Hospital for Sick Children, 555 University Ave, Toronto, ON, Canada M5G 1X8.
Pediatrics. 2010 Jun;125(6):e1518-22. doi: 10.1542/peds.2009-1829. Epub 2010 May 10.
Recognition of Crohn disease in children who present with cutaneous vulvar lesions as their initial clinical manifestation is often difficult. We report here the case of an 8-year-old girl with chronic vulvar edema, which on biopsy revealed granulomatous inflammation of the vulva. Further investigation and biopsy of the terminal ileum demonstrated similar findings and was consistent with a diagnosis of Crohn disease.
儿童以皮肤外阴病变为首发临床表现的克罗恩病常难以识别。我们在此报告 1 例 8 岁女孩慢性外阴水肿,其外阴活检示肉芽肿性炎症。进一步的末端回肠检查和活检显示类似发现,符合克罗恩病的诊断。