Department of Pediatrics and Adolescent Medicine, Division of General Pediatrics and Neonatology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Wien Klin Wochenschr. 2013 Jul;125(13-14):386-92. doi: 10.1007/s00508-013-0381-8. Epub 2013 Jul 2.
Identify factors for discrimination of "high" and "low risk" small for gestational age infants.
Singleton infants born small for gestational age with a birthweight <1,500 g between 1999 and 2007 were included. Maternal, placental, and infant related factors were analyzed with regard to mortality and morbidity. Patients who died or suffered from complications were defined "high risk" as opposed to "low risk". Parameters associated with "high risk" were identified and an equation established to predict the minimal expected probability to die or suffer from neonatal morbidity.
Around 231 patients showed a mortality rate of 12.6 %, respiratory distress syndrome in 35.5 %, necrotizing enterocolitis in 8.2 % and neurological morbidities in 6.5 %. Of these, 58.9 % survived without complications. The factors for discrimination of "high" and "low risk" were Z-score of birth weight, gestational age, and pH.
We facilitate prognostication by classifying small for gestational age preterms into "low" and "high risk".
确定鉴别“高危”和“低危”小于胎龄儿的因素。
本研究纳入了 1999 年至 2007 年间出生体重<1500g 的小于胎龄儿的单胎婴儿。分析了与母婴和婴儿相关的因素，包括死亡率和发病率。将死亡或患有并发症的患者定义为“高危”，与之相对的为“低危”。确定与“高危”相关的参数，并建立一个方程来预测死亡或新生儿发病率的最小预期概率。
约 231 例患儿死亡率为 12.6%，呼吸窘迫综合征为 35.5%，坏死性小肠结肠炎为 8.2%，神经系统疾病为 6.5%。其中，58.9%的患儿无并发症存活。鉴别“高危”和“低危”的因素是出生体重、胎龄和 pH 值的 Z 评分。
通过将小于胎龄儿早产儿分为“低危”和“高危”，我们可以进行预后评估。
