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Neck irradiation, carotid injury and its consequences.颈部照射、颈动脉损伤及其后果。
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Irradiation-induced extracranial carotid stenosis in patients with head and neck malignancies.头颈部恶性肿瘤患者的放疗诱发颅外颈动脉狭窄
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一名口底癌患者的放射性颈动脉狭窄

Radiation-induced carotid artery stenosis in a patient with carcinoma of the oral floor.

作者信息

Seto Kahori, Yamagata Kenji, Uchida Fumihiko, Yanagawa Toru, Onizawa Kojiro, Bukawa Hiroki

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba City, Ibaraki 305-8575, Japan.

出版信息

Case Rep Oncol Med. 2013;2013:379039. doi: 10.1155/2013/379039. Epub 2013 Jun 1.

DOI:10.1155/2013/379039
PMID:23819083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3683423/
Abstract

Radiation-induced carotid artery stenosis (RI-CS), a life-threatening condition, can occur after external radiation for head and neck cancer. We here describe a case of asymptomatic RI-CS in a 73-year-old patient treated with chemoradiotherapy and radical neck dissection for a basaloid squamous cell carcinoma of the oral floor. Stenosis of the left carotid artery, diagnosed as RI-CS, showed on an MRI performed 1.5 years after radiotherapy. Blood from the left side of the anterior cerebral artery and the middle anterior artery was flowing to the brain through the anterior and posterior communicating arteries, so no stent surgery or other treatment was necessary. The cancer has not recurred during approximately 5 years of followup after radiotherapy, and the patient has had no adverse effects from the RI-CS since it was diagnosed 3.5 years ago. This case emphasizes the necessity of early scrutiny for RI-CS in patients given radiotherapy for oral cancer.

摘要

放射性颈动脉狭窄（RI-CS）是一种危及生命的疾病，可发生于头颈部癌症的外照射放疗后。我们在此描述一例73岁患者的无症状RI-CS病例，该患者因口底基底样鳞状细胞癌接受了放化疗和根治性颈清扫术。放疗1.5年后进行的MRI显示左颈动脉狭窄，诊断为RI-CS。大脑前动脉左侧和大脑中动脉前部的血液通过前交通动脉和后交通动脉流向大脑，因此无需进行支架手术或其他治疗。放疗后约5年的随访期间癌症未复发，自3.5年前诊断出RI-CS以来，患者未出现该疾病的不良反应。该病例强调了对接受口腔癌放疗的患者进行RI-CS早期检查的必要性。