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Can acetaminophen excess result in maternal and fetal toxicity?

作者信息

Kurzel R B

机构信息

Department of Obstetrics and Gynecology, St. Louis University School of Medicine, St. Mary's Health Center, Mo.

出版信息

South Med J. 1990 Aug;83(8):953-5. doi: 10.1097/00007611-199008000-00023.

DOI:10.1097/00007611-199008000-00023
PMID:2382159
Abstract

This is the third case reported of maternal acetaminophen overdose during pregnancy. Such overdose may be associated with maternal liver toxicity. Fetal hepatotoxicity may be seen in association with maternal hepatotoxicity. As a result, the infant's blood coagulation times may be prolonged, and intracranial hemorrhage at delivery is a concern. Our case shows such a complication after chronic exposure to acetaminophen.

摘要

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