阿尔茨海默病的视觉表现：来自印度的基于临床的研究。
Visual manifestations in Alzheimer's disease: a clinic-based study from India.
机构信息
Department of Neurology, Burdwan Medical College, Burdwan, West Bengal, India.
出版信息
Am J Alzheimers Dis Other Demen. 2013 Sep;28(6):575-82. doi: 10.1177/1533317513494448. Epub 2013 Jul 2.
INTRODUCTION
Alzheimer's disease (AD) is characterized by amnesia, though non-memory-cognitive domains like visual are also affected. We planned to study frequency of visual dysfunctions in AD and their relationship with dementia severity.
MATERIALS AND METHODS
This study was conducted in the Cognitive clinic of Department of Neurology, Bangur Institute of Neurosciences, Kolkata, between January 2007 and December 2010. 55 patients of AD were evaluated by neurological and neuropsychological assessments and by special tests for visual dysfunctions.
RESULTS
Common visual dysfunctions were visuo-constructional (87.3%), visuo-perceptual (63.6%), object agnosia(47.3%), prosopagnosia (45.5%), visual hallucination (27.3%) and simultanagnosia (12.7%). Symptoms of ventral visual pathway dysfunction were more common than that of dorsal pathway. MMSE score and number of visual manifestations had a good correlation.
CONCLUSIONS
Visual dysfunctions are common in AD, elicitation of which helps us to understand the cause of disability so that appropriate steps can be taken.
简介
阿尔茨海默病（AD）的特征是健忘，尽管非记忆认知领域，如视觉，也受到影响。我们计划研究 AD 中视觉功能障碍的频率及其与痴呆严重程度的关系。
材料与方法
本研究于 2007 年 1 月至 2010 年 12 月在加尔各答班戈尔神经科学研究所神经内科认知诊所进行。对 55 例 AD 患者进行神经学和神经心理学评估，并进行特殊的视觉功能障碍检查。
结果
常见的视觉功能障碍包括视觉结构（87.3%）、视觉感知（63.6%）、物体认知障碍（47.3%）、面容失认症（45.5%）、视觉幻觉（27.3%）和同时性失认症（12.7%）。腹侧视觉通路功能障碍的症状比背侧通路更为常见。MMSE 评分和视觉表现的数量有很好的相关性。
结论
AD 中常见视觉功能障碍，对此类症状的评估有助于我们了解残疾的原因，以便采取适当的措施。
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