Lenoir Henri, Siéroff Éric
Institut de psychologie, Université de Paris, EA4468, Paris, France.
Geriatr Psychol Neuropsychiatr Vieil. 2019 Sep 1;17(3):307-316. doi: 10.1684/pnv.2019.0815.
Visual perception is humans' preferred way for taking information on the surrounding world. Visual perception is frequently impaired in patients with Alzheimer's disease, lessening patients' quality of life, and making evaluation of other cognitive deficits more complicated. Our review covers the recent literature describing visual perception deficits in patients suffering from Alzheimer's disease by classifying them according to their neuroanatomical correspondence: retina, visual pathway, subcortical structures, occipital visual cortex, occipito-temporal "what" and occipito-parietal "where" pathways. Overall, both low-level and high-level visual perception disorders seem quite common in Alzheimer's disease, including, on a low-level, loss of visual field, decreased acuity and contrast sensitivity, and impaired color vision, and on a high-level, impaired color vision, motion perception, visuospatial deficits, object agnosia, prosopagnosia and impaired recognition of facial emotional expressions. Professionals working with Alzheimer's disease should be aware of visuoperceptual deficits, which could impair the quality of life of the patients, and distort the results of neuropsychological tests using visual material. Moreover, some tests assessing visual perception could be of interest for early diagnosis of the disease.
视觉感知是人类获取周围世界信息的首选方式。阿尔茨海默病患者的视觉感知常常受损,这降低了患者的生活质量,并使对其他认知缺陷的评估更加复杂。我们的综述涵盖了近期描述阿尔茨海默病患者视觉感知缺陷的文献,根据其神经解剖学对应关系进行分类:视网膜、视觉通路、皮质下结构、枕叶视觉皮层、枕颞叶“是什么”通路和枕顶叶“在哪里”通路。总体而言,低水平和高水平的视觉感知障碍在阿尔茨海默病中似乎都很常见,在低水平方面包括视野缺损、视力下降和对比敏感度降低以及色觉受损,在高水平方面包括色觉受损、运动感知、视觉空间缺陷、物体失认症、面孔失认症以及对面部表情识别受损。从事阿尔茨海默病治疗工作的专业人员应意识到视觉感知缺陷,这可能会损害患者的生活质量,并扭曲使用视觉材料进行的神经心理学测试结果。此外,一些评估视觉感知的测试可能对该疾病的早期诊断有帮助。