Grunda Tomas, Marsalek Petr, Sykorova Pavla
Institute of Pathological Physiology, First Medical Faculty, Charles University in Prague, Prague, Czech Republic.
Acta Neurobiol Exp (Wars). 2013;73(2):237-49. doi: 10.55782/ane-2013-1933.
The term homonymous hemianopia refers to visual impairment due to a post-chiasmatic brain lesion. Mammalian neurons of the central nervous system do not have the ability to regenerate. However, the cerebral cortex shows plasticity in certain cases. Motor or speech disorders due to frontal lobe brain damage can be improved with well-directed rehabilitation techniques. If such plasticity is possible, it raises the question whether specialized training could improve a cortical visual disorder. There is need for simple visual training which could be used in rehabilitation. A few different approaches have been developed to treat patients with hemianopia: (1) substitution including special devices, such as optical prisms; (2) compensation using intact residual abilities - especially training of eye movements; (3) restitution which is based on stimulating the blind hemifield. The third method of rehabilitation is the most controversial; however, it has the largest potential. To support concepts of the targeted rehabilitation outlined here, first: further development of the theory of plasticity in visual pathways is required and second: the efficacy of the rehabilitation procedures has to be demonstrated by clinical evidence. We review methods and approaches of hemianopia rehabilitation and treatment. We also review results of contemporary clinical studies and meta-studies.
同向性偏盲这一术语指的是由于视交叉后脑部病变导致的视力障碍。中枢神经系统的哺乳动物神经元没有再生能力。然而,在某些情况下大脑皮层会表现出可塑性。额叶脑损伤导致的运动或言语障碍可以通过针对性的康复技术得到改善。如果这种可塑性是可能的,那么就会引发一个问题,即专门训练是否可以改善皮层性视觉障碍。需要有可用于康复的简单视觉训练。已经开发出几种不同的方法来治疗偏盲患者:(1)替代,包括使用特殊装置,如光学棱镜;(2)利用完好的残余能力进行补偿——特别是眼球运动训练;(3)基于刺激盲侧视野的恢复。第三种康复方法最具争议性;然而,它具有最大的潜力。为了支持此处概述的针对性康复理念,首先:需要进一步发展视觉通路可塑性理论;其次:康复程序的有效性必须有临床证据证明。我们回顾了偏盲康复和治疗的方法与途径。我们还回顾了当代临床研究和荟萃研究的结果。